Evidence map›Paper›PMID 27941676›Full record

ArticleMolecules (Basel, Switzerland)2016

Optimized and Automated Radiosynthesis of [

Wenjie Zhang, Zhengxin Cai, Lin Li, Jim Ropchan, Keunpoong Lim, Nabil E Boutagy, Jing Wu, John C Stendahl, Wenhua Chu, Robert Gropler and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Synthesis of a [Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  4. Review
  5. Feasibility study of PET dynamic imaging of [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  6. Molecular imaging of free radicals for anthracycline-induced cardiotoxicity: See the burn?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. Review
  8. Nuclear cardiology in the context of multimodality imaging to detect cardiac toxicity from cancer therapeutics: Established and emerging methods.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Wenjie ZhangDepartment of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu 610041, China. wenjie.zhang@yale.edu.
Zhengxin CaiPET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT 06520, USA. zhengxin.cai@yale.edu.
Lin LiDepartment of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu 610041, China. lilinhuaxi@sina.com.
Jim RopchanPET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT 06520, USA. jim.ropchan@yale.edu.
Keunpoong LimPET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT 06520, USA. keunpoong.lim@yale.edu.
Nabil E BoutagyDepartment of Medicine, Yale Translational Research Imaging Center, Yale School of Medicine, New Haven, CT 06520, USA. nabil.boutagy@yale.edu.
Jing WuPET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT 06520, USA. j.wu@yale.edu.
John C StendahlDepartment of Medicine, Yale Translational Research Imaging Center, Yale School of Medicine, New Haven, CT 06520, USA. john.stendahl@yale.edu.
Wenhua ChuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA. chuw@mir.wustl.edu.
Robert GroplerDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA. groplerr@mir.wustl.edu.
Albert J SinusasDepartment of Medicine, Yale Translational Research Imaging Center, Yale School of Medicine, New Haven, CT 06520, USA. albert.sinusas@yale.edu.
Chi LiuPET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT 06520, USA. chi.liu@yale.edu.
Yiyun HuangPET Center, Department of Radiology and Biomedical Imaging, Yale University, New Haven, CT 06520, USA. henry.huang@yale.edu.
Yale University · USImaging Center · USSichuan University · CNWashington University in St. Louis · US

Funding

Training In Multi-modality Molecular & Translational Cardiovascular ImagingT32HL098069 · NHLBI · YALE UNIVERSITY · PI JAMES S DUNCAN, Georges El Fakhri · 2010 to 2026
$5.2M
Low-dose SPECT/CT for imaging chemotherapy-induced microvascular cardiotoxicityR01HL123949 · NHLBI · YALE UNIVERSITY · PI LIU, CHI · 2014 to 2018
$3.2M
NHLBI NIH HHS R01 HL123949NHLBI NIH HHS T32 HL098069
6 · The paper itself

Abstract

Reactive oxygen species (ROS) play important roles in cell signaling and homeostasis. However, an abnormally high level of ROS is toxic, and is implicated in a number of diseases. Positron emission tomography (PET) imaging of ROS can assist in the detection of these diseases. For the purpose of clinical translation of [

Indexed as

Fluorine RadioisotopesRadiopharmaceuticalsAnimalsDogsPositron-Emission TomographyTranslational Research, BiomedicalFluorine RadioisotopesRadiopharmaceuticals2-[18F]fluoroethyl azideautomationin vivo imagingPETreactive oxygen speciestranslational study

Identifiers

PMID27941676
PMCPMC5505691
OpenAlexW2560710473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.