Evidence map›Paper›PMID 27941650›Full record

ReviewInternational journal of molecular sciences2016

Roles of Erythroid Differentiation Regulator 1 (Erdr1) on Inflammatory Skin Diseases.

Youn Kyung Houh, Kyung Eun Kim, Hyun Jeong Park, Daeho Cho

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Molecular Mechanisms of IL18 in Disease.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. FLUORESCENT LIGHT ENERGY: The Future for Treating Inflammatory Skin Conditions?The Journal of clinical and aesthetic dermatology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Youn Kyung HouhDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea. bobada6025@gmail.com.
Kyung Eun KimDepartment of Cosmetic Sciences, Sookmyung Women's University, Seoul 04310, Korea. kyungeun@sookmyung.ac.kr.
Hyun Jeong ParkDepartment of Dermatology, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul 07345, Korea. hjpark@catholic.ac.kr.
Daeho ChoDepartment of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea. cdhkor@sookmyung.ac.kr.
Sookmyung Women's University · KRThe Catholic University of Korea Yeouido St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erythroid Differentiation Regulator 1 (Erdr1) is known as a hemoglobin synthesis factor which also regulates cell survival under conditions of stress. In addition, previous studies have revealed the effects of Erdr1 on cancer progression and its negative correlation with interleukin (IL)-18, a pro-inflammatory cytokine. Based on this evidence, the therapeutic effects of Erdr1 have been demonstrated in several inflammatory skin diseases such as malignant skin cancer, psoriasis, and rosacea. This article reviews the roles of Erdr1 in skin inflammation, suggesting that Erdr1 is a potential therapeutic molecule on inflammatory disorders.

Indexed as

HumansInflammationModels, BiologicalMolecular Targeted TherapySkin DiseasesTumor Suppressor ProteinsTumor Suppressor Proteinscutaneous inflammationErdr1IL-18melanomapsoriasisrosacea

Identifiers

PMID27941650
PMCPMC5187859
OpenAlexW2560650892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.