Evidence map›Paper›PMID 27941621›Full record

ArticleInternational journal of molecular sciences2016

Relevance of MicroRNA200 Family and MicroRNA205 for Epithelial to Mesenchymal Transition and Clinical Outcome in Biliary Tract Cancer Patients.

Romana Urbas, Christian Mayr, Eckhard Klieser, Julia Fuereder, Doris Bach, Stefan Stättner, Florian Primavesi, Tarkan Jaeger, Stefanie Stanzer, Anna Lena Ress and 7 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  6. Observational
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Romana UrbasInstitute of Pathology, Paracelsus Medical University/Salzburger Landeskliniken (SALK), Salzburg 5020, Austria. r.urbas@salk.at.
Christian MayrLaboratory for Tumour Biology and Experimental Therapies (TREAT), Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg 5020, Austria. christian.mayr@pmu.ac.at.
Eckhard KlieserInstitute of Pathology, Paracelsus Medical University/Salzburger Landeskliniken (SALK), Salzburg 5020, Austria. e.klieser@salk.at.
Julia FuerederDepartment of Internal Medicine I, Paracelsus Medical University/Salzburger Landeskliniken (SALK), Salzburg 5020, Austria. j.fuereder@gmx.net.
Doris BachDepartment of Internal Medicine I, Paracelsus Medical University/Salzburger Landeskliniken (SALK), Salzburg 5020, Austria. doris.bach@gmx.at.
Stefan StättnerDepartment of Visceral-, Transplant- and Thoracic Surgery, Medical University of Innsbruck, Innsbruck 6020, Austria. stefan.staettner@tirol-kliniken.at.
Florian PrimavesiDepartment of Visceral-, Transplant- and Thoracic Surgery, Medical University of Innsbruck, Innsbruck 6020, Austria. florian.primavesi@tirol-kliniken.at.
Tarkan JaegerDepartment of Surgery, Paracelsus Medical University/Salzburger Landeskliniken (SALK), Salzburg 5020, Austria. ta.jaeger@salk.at.
Stefanie StanzerResearch Unit for Non-Coding RNA and Genome Editing in Cancer, Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz 8036, Austria. Stefanie.Stanzer@klinikum-graz.at.
Anna Lena RessResearch Unit for Non-Coding RNA and Genome Editing in Cancer, Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz 8036, Austria. anna.lena.ress@gmail.com.
Magdalena LöffelbergerLaboratory for Tumour Biology and Experimental Therapies (TREAT), Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg 5020, Austria. mloeffelberger.bma-b2012@fh-salzburg.ac.at.
Andrej WagnerDepartment of Internal Medicine I, Paracelsus Medical University/Salzburger Landeskliniken (SALK), Salzburg 5020, Austria. and.wagner@salk.at.
Frieder BerrLaboratory for Tumour Biology and Experimental Therapies (TREAT), Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg 5020, Austria. frieder.berr@pmu.ac.at.
Markus RitterLaboratory for Tumour Biology and Experimental Therapies (TREAT), Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg 5020, Austria. markus.ritter@pmu.ac.at.
Martin PichlerResearch Unit for Non-Coding RNA and Genome Editing in Cancer, Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz 8036, Austria. martin.pichler@medunigraz.at.
Daniel NeureiterInstitute of Pathology, Paracelsus Medical University/Salzburger Landeskliniken (SALK), Salzburg 5020, Austria. d.neureiter@salk.at.
Tobias KiesslichLaboratory for Tumour Biology and Experimental Therapies (TREAT), Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg 5020, Austria. t.kiesslich@salk.at.
Paracelsus Medical University · ATMedical University of Graz · ATInnsbruck Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extensive stromal interaction is one reason for the dismal outcome of biliary tract cancer (BTC) patients. Epithelial to mesenchymal transition (EMT) is involved in tumor invasion and metastasis and is partly regulated by microRNAs (miRs). This study explores the expression of anti-EMT miR200 family (miR141, -200a/b/c, -429) and miR205 as well as the EMT-related proteins

Indexed as

Biliary Tract NeoplasmsCell Line, TumorEpithelial-Mesenchymal TransitionFemaleGene Expression Regulation, NeoplasticHumansMicroRNAsRNA, MessengerMicroRNAsRNA, Messengerbiliary tract cancerepithelial to mesenchymal transitionmicroRNA-200 familymicroRNA-205

Identifiers

PMID27941621
PMCPMC5187853
OpenAlexW2560592895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.