Senescence associated macrophages and "macroph-aging": are they pieces of the same puzzle?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

49 citing papers in PubMed.

1. Liver Macrophages in the Pathogenesis of Viral Hepatitis.Current issues in molecular biology · 2026
   Review
2. Integrative Omics Reveal Female-Specific Benefits of p16Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
   Article
3. Aging-Related Mechanisms Underlying Carcinogenesis: Therapeutic Opportunities.Aging and disease · 2025
   Review
4. Macrophage Changes and High-Throughput Sequencing in Aging Mouse Intervertebral Disks.JOR spine · 2025
   Article
5. Natural killer cell-based senotherapy: a promising strategy for healthy aging.Frontiers in immunology · 2025
   Review
6. Age and liver transplantation: a key factor in clinical outcomes? single center study in Argentina.Frontiers in aging · 2025
   Article
7. Senescent Macrophages and the Lung Cancer Microenvironment: A New Perspective on Tumor Immune Evasion.Aging and disease · 2024
   Review
8. Genetic origins, regulators, and biomarkers of cellular senescence.Trends in genetics : TIG · 2024
   Review
9. Advancements in Targeting Macrophage Senescence for Age-Associated Conditions.Aging and disease · 2024
   Review
10. Aging and chronic kidney disease: epidemiology, therapy, management and the role of immunity.Clinical kidney journal · 2024
    Review
11. Multiparametric identification of putative senescent cells in skeletal muscle via mass cytometry.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2024
    Article
12. Immunomodulatory effects of cannabinoids against viral infections: a review of its potential use in SARS-CoV2 infection.Virusdisease · 2024
    Review
13. Autonomic nervous system imbalance during aging contributes to impair endogenous anti-inflammaging strategies.GeroScience · 2024
    Review
14. Senescent alveolar macrophages promote early-stage lung tumorigenesis.Cancer cell · 2023
    Article
15. Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging.Aging cell · 2023
    Article
16. Macrophages and Bone Remodeling.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
    Review
17. Macrophages and Intervertebral Disc Degeneration.International journal of molecular sciences · 2023
    Review
18. Mitochondrial dysfunction at the cornerstone of inflammatory exacerbation in aged macrophages.Exploration of immunology · 2023
    Article
19. cGAS-STING pathway as a potential trigger of immunosenescence and inflammaging.Frontiers in immunology · 2023
    Review
20. The diseased kidney: aging and senescent immunology.Immunity & ageing : I & A · 2022
    Review

Corrections and comments

• Comment on
  Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells.2016

Authors and funding

4 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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