Evidence map›Paper›PMID 27941122›Full record

ArticleMolecular imaging2016

First PET Imaging Studies With 63Zn-Zinc Citrate in Healthy Human Participants and Patients With Alzheimer Disease.

Timothy R DeGrado, Bradley J Kemp, Mukesh K Pandey, Huailei Jiang, Tina M Gunderson, Logan R Linscheid, Allison R Woodwick, Daniel M McConnell, Joel G Fletcher, Geoffrey B Johnson and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Impact of anFrontiers in endocrinology · 2023
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Role of GPR39 in Neurovascular Homeostasis and Disease.International journal of molecular sciences · 2021
    Review
  10. Review
  11. Production of radiometals in liquid targets.EJNMMI radiopharmacy and chemistry · 2020
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Insights into Trace Metal Metabolism in Health and Disease from PET: "PET Metallomics".Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2018
    Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Timothy R DeGradoDepartment of Radiology, Mayo Clinic, Rochester, MN, USA degrado.timothy@mayo.edu.
Bradley J KempDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Mukesh K PandeyDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Huailei JiangDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Tina M GundersonDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Logan R LinscheidDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Allison R WoodwickDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Daniel M McConnellDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Joel G FletcherDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Geoffrey B JohnsonDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Ronald C PetersenDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
David S KnopmanDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Val J LoweDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Arizona · USMayo Clinic in Florida · US

Funding

THE PGRN/TDP-43 AXIS IN ALZHEIMER?S DISEASE AND NEURODEGENERATIONP50AG016574 · NIA · MAYO CLINIC ROCHESTER · PI BU, GUOJUN · 1999 to 2018
$36.9M
NIA NIH HHS P50 AG016574
6 · The paper itself

Abstract

Abnormalities in zinc homeostasis are indicated in many human diseases, including Alzheimer disease (AD).

Indexed as

AgedAged, 80 and overAlzheimer DiseaseBrainCitratesFemaleFluorodeoxyglucose F18Healthy VolunteersHumansMaleMiddle AgedPositron-Emission TomographyRadiopharmaceuticalsTissue DistributionUrineZinc RadioisotopesCitratesFluorodeoxyglucose F18RadiopharmaceuticalsZinc Radioisotopes63ZnAlzheimer diseasePETzinc homeostasis

Identifiers

PMID27941122
PMCPMC5469518
OpenAlexW2559895286

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.