Evidence map›Paper›PMID 27940756›Full record

ArticlePediatrics2016

Complementary and Alternative Medicine and Influenza Vaccine Uptake in US Children.

William K Bleser, Bilikisu Reni Elewonibi, Patricia Y Miranda, Rhonda BeLue

Open access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

William K BleserDepartment of Health Policy and Administration, Pennsylvania State University, University Park, Pennsylvania.
Bilikisu Reni ElewonibiDepartment of Health Policy and Administration, Pennsylvania State University, University Park, Pennsylvania.
Patricia Y MirandaDepartment of Health Policy and Administration, Pennsylvania State University, University Park, Pennsylvania.
Rhonda BeLueDepartment of Health Policy and Administration, Pennsylvania State University, University Park, Pennsylvania rzb10@psu.edu.
Pennsylvania State University · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
Population Research InstituteR24HD041025 · NICHD · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI MATTHEWS, STEPHEN A · 2001 to 2016
$9.7M
The Population Research Institute: Development CoreP2CHD041025 · NICHD · PENNSYLVANIA STATE UNIVERSITY, THE · PI Brian Thiede · 2016 to 2026
$9.0M
Penn State Institutional Career Development CoreKL2TR002015 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI VAN SCOY, LAUREN JODI · 2016 to 2025
$7.8M
Penn State Clinical and Translational Science InstituteKL2TR000126 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$3.2M
NCATS NIH HHS KL2 TR000126NCATS NIH HHS KL2 TR002015NCATS NIH HHS UL1 TR000127NCATS NIH HHS UL1 TR002014NICHD NIH HHS P2C HD041025NICHD NIH HHS R24 HD041025
6 · The paper itself

Abstract

backgroundComplementary and alternative medicine (CAM) is increasingly used in the United States. Although CAM is mostly used in conjunction with conventional medicine, some CAM practitioners recommend against vaccination, and children who saw naturopathic physicians or chiropractors were less likely to receive vaccines and more likely to get vaccine-preventable diseases. Nothing is known about how child CAM usage affects influenza vaccination.

methodsThis nationally representative study analyzed ∼9000 children from the Child Complementary and Alternative Medicine File of the 2012 National Health Interview Survey. Adjusting for health services use factors, it examined influenza vaccination odds by ever using major CAM domains: (1) alternative medical systems (AMS; eg, acupuncture); (2) biologically-based therapies, excluding multivitamins/multiminerals (eg, herbal supplements); (3) multivitamins/multiminerals; (4) manipulative and body-based therapies (MBBT; eg, chiropractic manipulation); and (5) mind-body therapies (eg, yoga).

resultsInfluenza vaccination uptake was lower among children ever (versus never) using AMS (33% vs 43%; P = .008) or MBBT (35% vs 43%; P = .002) but higher by using multivitamins/multiminerals (45% vs 39%; P < .001). In multivariate analyses, multivitamin/multimineral use lost significance, but children ever (versus never) using any AMS or MBBT had lower uptake (respective odds ratios: 0.61 [95% confidence interval: 0.44-0.85]; and 0.74 [0.58-0.94]).

conclusionsChildren who have ever used certain CAM domains that may require contact with vaccine-hesitant CAM practitioners are vulnerable to lower annual uptake of influenza vaccination. Opportunity exists for US public health, policy, and medical professionals to improve child health by better engaging parents of children using particular domains of CAM and CAM practitioners advising them.

Indexed as

AdolescentChildChild, PreschoolComplementary TherapiesEducational StatusFemaleHealth SurveysHumansInfluenza VaccinesMaleMultivariate AnalysisRacial GroupsUnited StatesVaccinationVitaminsInfluenza VaccinesVitamins

Identifiers

PMID27940756
PMCPMC5079075
OpenAlexW2529028882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.