ArticleApplied and environmental microbiology2017
Influences of pH and Iron Concentration on the Salivary Microbiome in Individual Humans with and without Caries.
Article in Applied and environmental microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Salivary elemental signature of dental caries: a systematic review and meta-analysis of ionomics studies.Odontology · 2024Pooled it
- Effects of Fluoride and Calcium Phosphate-Based Varnishes in Children at High Risk of Tooth Decay: A Randomized Clinical Trial.International journal of environmental research and public health · 2021Trial
- Oral-gut microbiome dysbiosis in obese smokers reveals compartment-specific shifts.AMB Express · 2026Article
- Effects of pica practice on oral bacteriome and mycobiome profiles among pregnant women: A comparative study.PloS one · 2026Article
- The Relationship between Age, Gender, BMI, Diet, Salivary pH and Periodontal Pathogenic Bacteria in Children and Adolescents: A Cross-Sectional Study.Biomedicines · 2023Article
- Participants in the Trans-Antarctic Winter Traverse Expedition Showed Increased Bacterial Load and Diversity in Saliva but Maintained Individual Differences within Stool Microbiota and Across Metabolite Fingerprints.International journal of molecular sciences · 2023Article
- Oral manifestations of iron imbalance.Frontiers in nutrition · 2023Article
- Oralbiotica/Oralbiotics: The Impact of Oral Microbiota on Dental Health and Demineralization: A Systematic Review of the Literature.Children (Basel, Switzerland) · 2022Review
- Impact of sucroferric oxyhydroxide on the oral and intestinal microbiome in hemodialysis patients.Scientific reports · 2022Article
- Article
- Comparison of the Oral Microbiota Structure among People from the Same Ethnic Group Living in Different Environments.BioMed research international · 2022Article
- Probiotic Effects of Lactobacillus paracasei 28.4 to Inhibit Streptococcus mutans in a Gellan-Based Formulation.Probiotics and antimicrobial proteins · 2021Article
- Relationship between dental and periodontal health status and the salivary microbiome: bacterial diversity, co-occurrence networks and predictive models.Scientific reports · 2021Article
- Salivary microbiome composition changes after bariatric surgery.Scientific reports · 2020Article
- Nitrate as a potential prebiotic for the oral microbiome.Scientific reports · 2020Article
- Analysis of by high-throughput sequencing: Helicobacter pylori infection and salivary microbiome.BMC oral health · 2020Article
- FBA Ecological Guild: Trio of Firmicutes-Bacteroidetes Alliance against Actinobacteria in Human Oral Microbiome.Scientific reports · 2020Article
- The microbial abundance dynamics of the paediatric oral cavity before and after sleep.Journal of oral microbiology · 2020Article
- Article
- Risk factors for the presence of dental black plaque.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to identify the differences in the oral microbial communities in saliva from patients with and without caries by performing sequencing with the Illumina MiSeq platform, as well as to further assess their relationships with environmental factors (salivary pH and iron concentration). Forty-three volunteers were selected, including 21 subjects with and 22 without caries, from one village in Gansu, China. Based on 966,255 trimmed sequences and clustering at the 97% similarity level, 1,303 species-level operational taxonomic units were generated. The sequencing data for the two groups revealed that (i) particular distribution patterns (synergistic effects or competition) existed in the subjects with and without caries at both the genus and species levels and (ii) both the salivary pH and iron concentration had significant influences on the microbial community structure. IMPORTANCE: The significant influences of the oral environment observed in this study increase the current understanding of the salivary microbiome in caries. These results will be useful for expanding research directions and for improving disease diagnosis, prognosis, and therapy.
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