ReviewCold Spring Harbor perspectives in biology2017
Tau Positron Emission Tomography Imaging.
Review in Cold Spring Harbor perspectives in biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- A Cooperative Model for Symmetric Ligand Binding to Protein Fibrils.Biochemistry · 2025Article
- A Cooperative Model for Symmetric Ligand Binding to Protein Fibrils.bioRxiv : the preprint server for biology · 2025Article
- Alzheimer's disease: where do we stand now and what are the strategic interventions?Frontiers in cellular neuroscience · 2025Review
- Advancing Tau PET Quantification in Alzheimer Disease with Machine Learning: Introducing THETA, a Novel Tau Summary Measure.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024Article
- A review of the flortaucipir literature for positron emission tomography imaging of tau neurofibrillary tangles.Brain communications · 2024Review
- The Sensitivity of Tau Tracers for the Discrimination of Alzheimer's Disease Patients and Healthy Controls by PET.Biomolecules · 2023Review
- Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Tracers progress for positron emission tomography imaging of glial-related disease.Journal of biomedical research · 2022Article
- Worsening hearing was associated with higher β-amyloid and tau burden in age-related hearing loss.Scientific reports · 2022Article
- Rational design and synthesis of a novel BODIPY-based probe for selective imaging of tau tangles in human iPSC-derived cortical neurons.Scientific reports · 2022Article
- Tau Protein Binding Modes in Alzheimer's Disease for Cationic Luminescent Ligands.The journal of physical chemistry. B · 2021Article
- Positron Emission Tomography (PET) and Neuroimaging in the Personalized Approach to Neurodegenerative Causes of Dementia.International journal of molecular sciences · 2020Review
- PET Radiopharmaceuticals for Alzheimer's Disease and Parkinson's Disease Diagnosis, the Current and Future Landscape.Molecules (Basel, Switzerland) · 2020Review
- Evaluation of [ACS chemical neuroscience · 2020Article
- Molecular Imaging of Tau Protein: New Insights and Future Directions.Frontiers in molecular neuroscience · 2020Review
- Molecular biomarkers of Alzheimer's disease: progress and prospects.Disease models & mechanisms · 2018Review
- Quantification of brain cholinergic denervation in Alzheimer's disease using PET imaging with [Molecular psychiatry · 2017Article
- Article
- Pathology of Neurodegenerative Diseases.Cold Spring Harbor perspectives in biology · 2017Review
- A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies.Trends in pharmacological sciences · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the most common cause of dementia among the elderly population. The good correlation between the density and neocortical spread of neurofibrillary tangles (NFTs) and the severity of cognitive impairment offers an opportunity to use a noninvasive imaging technique such as positron emission tomography (PET) for early diagnosis and staging of the disease. PET imaging of NFTs holds promise not only as a diagnostic tool but also because it may enable the development of disease-modifying therapeutics for AD. In this review, we focus on the structural diversity of tau PET tracers, the challenges related to identifying high-affinity and highly selective NFT ligands, and recent progress in the clinical development of tau PET radioligands.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.