ReviewBritish journal of anaesthesia2016
Perioperative cognitive protection.
Review in British journal of anaesthesia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Association Between Minor Brain Injuries and Level of Anesthesia Detected by a New EEG Based Tool, to Delirium and Post-operative Cognitive Dysfunction After Cardiac and Non-cardiac Surgery - a Proof of Concept Study
Assessing Brain Frailty; The Association Between Pre, Intra and Post-operative Electrophysiological Markers and Postoperative Cognitive Dysfunction
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cognitive dysfunction in older patients undergoing non-neurosurgery in the immediate postoperative period: A systematic review.Nursing open · 2024Pooled it
- Pooled it
- Subjective cognitive complaints in patients undergoing major non-cardiac surgery: a prospective single centre cohort trial.British journal of anaesthesia · 2019Trial
- Long-Term Cognitive and Functional Outcomes of Anesthesia and Surgery in Patients with Dementia.Healthcare (Basel, Switzerland) · 2026Review
- Grip strength as a simple method to predict postoperative delirium after lower extremity surgery in the elderly: a prospective diagnostic evaluation.Anesthesia and pain medicine · 2026Article
- Article
- Cognitive Impairment Before Cardiac Surgery: A Prospective Single-Center Observational Analysis.Journal of clinical medicine · 2025Article
- Comparison of Fentanyl, Ketamine, and Lidocaine Combined with Propofol Anesthesia in Patients with Crohn Disease Undergoing Colonoscopy.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Postoperative delirium: identifying the patient at risk and altering the course: A narrative review.European journal of anaesthesiology and intensive care · 2023Review
- Review
- Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor.Journal of neuroinflammation · 2022Article
- Effect of Dexmedetomidine on Early Postoperative Cognitive Function in Patients Undergoing Arthroscopic Shoulder Surgery in Beach Chair Position: A Randomized Double-Blind Study.Journal of clinical medicine · 2022Article
- Does cognitive frailty predict delayed neurocognitive recovery after noncardiac surgery in frail elderly individuals? Probably not.Frontiers in aging neuroscience · 2022Article
- Identification of individuals at risk for postoperative cognitive dysfunction (POCD).Therapeutic advances in neurological disorders · 2022Review
- Association between preoperative serum homocysteine and delayed neurocognitive recovery after non-cardiac surgery in elderly patients: a prospective observational study.Perioperative medicine (London, England) · 2021Article
- Preoperative opioid, sedative, and antidepressant use is associated with increased postoperative hospital costs in colorectal surgery.Surgical endoscopy · 2021Article
- Intranasal Insulin Administration to Prevent Delayed Neurocognitive Recovery and Postoperative Neurocognitive Disorder: A Narrative Review.International journal of environmental research and public health · 2021Review
- A prospective observational cohort pilot study of the association between midazolam use and delirium in elderly endoscopy patients.BMC anesthesiology · 2021Observational
- Increased Serum Neuropeptide Galanin Level Is a Predictor of Cognitive Dysfunction in Patients with Hip Fracture.Disease markers · 2021Observational
- D-Amphetamine Rapidly Reverses Dexmedetomidine-Induced Unconsciousness in Rats.Frontiers in pharmacology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
There is significant evidence that many older surgical patients experience at least a transient decrease in cognitive function. Although there is still equipoise regarding the degree, duration, and mechanism of cognitive dysfunction, there is a concurrent need to provide best-practice clinical evidence. The two major cognitive disorders seen after surgery are postoperative delirium and postoperative cognitive dysfunction. Delirium is a public health problem; millions of dollars are spent annually on delirium-related medical resource use and prolonged hospital stays. Postoperative cognitive dysfunction is a research construct that historically signifies decline in performance on a neuropsychiatric test or group of tests and begins days to weeks after surgery. This review focuses on the current state of information gathered by several interdisciplinary stakeholder groups. Although there is still a need for high-level evidence to guide clinical practice, there is an emerging literature that can guide practitioners.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.