ReviewCurrent opinion in microbiology2017
Viral-bacterial co-infections in the respiratory tract.
Review in Current opinion in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05929599 (Efficacy of Nasal-sprayed Probiotics Containing Bacillus Subtilis and Bacillus Clausii), which is not on this map. Cited by 125 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Nasal-sprayed Probiotics Containing Bacillus Subtilis and Bacillus Clausii (LiveSpo Navax) in the Supportive Treatment of Pneumonia in Children Infected With Viral Respiratory Syncytial Virus (RSV) and Bacterial Co-infections
Who cites it
125 citing papers in PubMed, 2 syntheses or guidelines pooled it, 201 citations in OpenAlex.
- Effect of Pneumococcal Conjugate Vaccines on Viral Respiratory Infections: A Systematic Literature Review.The Journal of infectious diseases · 2024Pooled it
- Meta-Analysis of the Diagnostic Efficacy of the Luminex xTAG Respiratory Viral Panel FAST v2 Assay for Respiratory Viral Infections.Yonsei medical journal · 2022Pooled it
- A case-control study of the causes of acute respiratory infection among hospitalized patients in Northeastern Laos.Scientific reports · 2022Trial
- A decade of endemic human coronaviruses: epidemiological patterns and clinical significance in an adult cohort at a tertiary care hospital in Germany.BMC infectious diseases · 2026Article
- An Appraisal of the Potential Downstream Benefits of RSV Vaccination in Older Adults.Reviews in medical virology · 2026Review
- Associated factors of microorganisms causing lower respiratory tract infections in children hospitalized between 2019 and 2022 in a private hospital in Lima, PerúBiomedica : revista del Instituto Nacional de Salud · 2026Article
- Predicting the burden of co-infections in seasonally driven dynamics of pediatric rotavirus and norovirus.Infectious Disease Modelling · 2026Article
- Article
- Epidemiological characteristics of human parainfluenza virus infection in hospitalized children: a single-center study.Frontiers in public health · 2026Article
- The temporal sequence of influenza H1N1 andFrontiers in microbiology · 2026Article
- Comparative progress on the mechanisms of airway mucosal injury induced by different pathogens: SARS-CoV-2, influenza A virus, and Mycoplasma pneumoniae.Frontiers in cellular and infection microbiology · 2026Review
- Epidemiology and co-infection networks of pediatric respiratory pathogens in eastern China after COVID-19 restriction relaxation: a retrospective study.Frontiers in cellular and infection microbiology · 2026Article
- Comparative epidemiology of six respiratory pathogens among children aged 28 days to 14 years with acute respiratory infections in coastal Xiamen and inland Linxia, China: a multicenter retrospective study.Frontiers in public health · 2026Article
- Changing patterns of respiratory pathogens in hospitalized children with community-acquired pneumonia in northern China following the lifting of non-pharmaceutical interventions.Microbiology spectrum · 2025Observational
- COVID-19 and Influenza Deaths in Australian Children 2018-2023: A National Case Analysis.Journal of the Pediatric Infectious Diseases Society · 2025Article
- Management of Infants Treated for Respiratory Viral Infections: A Finnish Retrospective Register-Based Study.Health science reports · 2025Article
- Impact of Antibiotic Exposure on Pediatric Drug Eruption: A Nationwide Cohort Study in Korea.Allergy, asthma & immunology research · 2025Article
- Clinical characteristics and influencing factors of severe influenza A virus pneumonia in children coinfected with gram-negative bacteria: A retrospective analysis.The Journal of international medical research · 2025Article
- Impact of the corona virus disease 2019 pandemic on the prevalence of common respiratory pathogens in hospitalized young patients with non-severe community-acquired pneumonia.Journal of thoracic disease · 2025Article
- Detection of respiratory pathogens in infants using targeted next-generation sequencing versus conventional methods in Qingdao.BMC infectious diseases · 2025Article
65 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preceding or concurrent viral respiratory tract infection can predispose to secondary bacterial co-infection throughout the airway. The mechanisms by which viruses promote these superinfections are diverse and replete. Whereas we understand much as to how viruses damage the airway and dysregulate both innate and acquired immune responses which, in turn, supports bacterial growth, adherence and invasion into normally sterile sites within the respiratory tract, new information regarding these co-infections is being gained from recent advances in microbiome research and our enhanced appreciation of the contribution of bacterial biofilms, among others. The advanced understanding obtained by continued research efforts in all aspects of viral-bacterial co-infections of the respiratory tract will allow us to devise novel approaches for disease prevention as well as to develop more effective therapeutics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.