ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2017
Effect of Exercise and Antidepressants on Skeletal Outcomes in Adolescent Girls With Anorexia Nervosa.
Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00310791 (Effects of Adrenal and Gonadal Hormone Replacement in Young Women With Anorexia Nervosa), which is not on this map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Adrenal and Gonadal Hormone Replacement in Young Women With Anorexia Nervosa
Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Effect of Transdermal Estradiol and Insulin-like Growth Factor-1 on Bone Endpoints of Young Women With Anorexia Nervosa.The Journal of clinical endocrinology and metabolism · 2021Trial
- Article
- Subjective Experience of Antidepressant Prescription Among Adolescents With Anorexia Nervosa.Frontiers in psychiatry · 2022Article
- Associations between exercise, bone mineral density, and body composition in adolescents with anorexia nervosa.Eating and weight disorders : EWD · 2019Article
- Low bone mineral density in anorexia nervosa: Treatments and challenges.Clinical reviews in bone and mineral metabolism · 2019Article
- Effects of Anorexia Nervosa on Bone Metabolism.Endocrine reviews · 2018Review
- The Impact of Psychotropic Medications on Bone Health in Youth.Current psychiatry reports · 2018Review
- Role of antidepressants in the treatment of adults with anorexia nervosa.The mental health clinician · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
purposeWe examined the relationships between malnutrition, lifestyle factors, and bone health in anorexia nervosa (AN) via dual-energy X-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT).
methodsSeventy adolescent girls with AN and 132 normal-weighted controls underwent pQCT tibial measures including trabecular volumetric bone mineral density (vBMD), cortical vBMD, and cortical thickness. Participants with AN underwent DXA measures of the axial skeleton. We assessed the association of DXA and pQCT measures with clinical and lifestyle variables.
resultsBody mass index Z-score and ideal body weight percentage were positively correlated with trabecular vBMD, cortical CSA, and section modulus (p < .04). Exercise was associated with all pQCT measures but only with hip BMD by DXA. In AN, the use of antidepressants was associated with lower pQCT measures (p < .03).
conclusionsAntidepressants may negatively, and exercise positively, influence BMD in adolescents with eating disorders. These findings offer a provocative look at two longstanding questions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.