ArticlePregnancy hypertension2016
Hypertensive disease in pregnancy in Botswana: Prevalence and impact on perinatal outcomes.
Article in Pregnancy hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Prevalence of hypertensive disorders of pregnancy and pregnancy outcomes in Sub-Saharan Africa: A systematic review and meta-analysis.Women's health (London, England)Pooled it
- Anti-hypertensive use for non-severe gestational hypertension in Botswana: A case-control study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022Trial
- Prevalence, trends, and subtype-specific outcomes of hypertensive disorders in pregnancy in China: data from 18 million pregnant women in a hospitalization-based retrospective study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Safety of Antihypertensive Medication for the Management of Non-Severe Gestational Hypertension Among Pregnant Individuals in Botswana-Emulating a Series of Target Trials.Paediatric and perinatal epidemiology · 2026Article
- The association between 2017 American College of Cardiology/American Heart Association guideline for hypertension and neonatal outcomes in Kenya: a retrospective study.Tropical medicine and health · 2025Article
- Article
- Low prevalence of high blood pressure in pregnant women in Burkina Faso: a cross-sectional study.BMC pregnancy and childbirth · 2022Article
- The effect of preeclampsia on adverse maternal outcomes in Sidama region, Ethiopia: a prospective open cohort study.Scientific reports · 2022Article
- A Scoping Review of Preterm Births in Sub-Saharan Africa: Burden, Risk Factors and Outcomes.International journal of environmental research and public health · 2022Article
- Comparison of Clinical Pregnancy Outcomes after Fresh and Frozen Embryo Transfer.Computational and mathematical methods in medicine · 2022Article
- Placental Decidual Arteriopathy and Vascular Endothelial Growth Factor A Expression Among Women With or Without Human Immunodeficiency Virus.The Journal of infectious diseases · 2021Article
- Review
- Adverse Effects of Exposure to Fine Particulate Matters and Ozone on Gestational Hypertension.Current medical science · 2019Article
- Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesPerinatal morbidity in sub-Saharan Africa has been attributed to infection, obstetric emergencies, and preterm birth, but less is known about hypertension in pregnancy. Our objective was to characterize the prevalence of hypertension in pregnancy and the impact of hypertension on perinatal outcomes in sub-Saharan Africa. STUDY
designWe performed surveillance of obstetric records at eight of the largest public hospitals in Botswana. Women were included in this analysis if they were HIV-uninfected and had singleton gestations and at least one prenatal blood pressure measurement.
main outcome measuresWe measured stillbirth, preterm birth, small for gestational age, and neonatal death in women with and without hypertension in pregnancy.
resultsWe included 14,170 pregnancies. Hypertension occurred in 3156 (22.2%) women, with 602 (19.1%) defined as severe. Severe hypertension increased risk of stillbirth (RR 4.4; 95% CI 3.2-6.2), preterm birth (RR 2.5; 95% CI 2.2-2.8), small for gestational age (RR 2.7; 95% CI 2.3-3.1) and neonatal death (RR 5.1; 95% CI 2.9-5.6). Non-severe hypertension increased risk of stillbirth (RR 2.0; 95% CI 1.5-2.7), preterm birth (RR 1.2; 95% CI 1.1-1.3), and small for gestational age (RR 1.6; 95% CI 1.4-1.8). Perinatal outcomes were worse in women with hypertension who had spontaneous preterm birth compared to those who underwent iatrogenic preterm delivery.
conclusionsHypertension in pregnancy is common in Botswana and leads to a large number of adverse outcomes. Improved management of hypertension in pregnancy may improve perinatal morbidity and mortality.
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