Evidence map›Paper›PMID 27938498›Full record

Trial reportCell transplantation2017

Adiponectin Potentially Contributes to the Antidepressive Effects of Baduanjin Qigong Exercise in Women With Chronic Fatigue Syndrome-Like Illness.

Jessie S M Chan, Ang Li, Siu-Man Ng, Rainbow T H Ho, Aimin Xu, Tzy-Jyun Yao, Xiao-Min Wang, Kwok-Fai So, Cecilia L W Chan

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Cell transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06490250 (Comparison of the Effects of Inspiratory Muscle Training and Baduanjin Exercises on Pulmonary Function, Exercise Capacity and Quality of Life in Patients With Hypertrophic Cardiomyopathy), which is not on this map. Cited by 31 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 8 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06490250 narecruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of the Effects of Inspiratory Muscle Training and Baduanjin Exercises on Pulmonary Function, Exercise Capacity and Quality of Life in Patients With Hypertrophic Cardiomyopathy

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2024 to 2025Enrolled51ConditionsHypertrophic Cardiomyopathy, Heart DiseasesArmsInspiratory Muscle Training, Baduanjin Exercise
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 8 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
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  9. Trial
  10. The Effects of Tai Chi on Heart Rate Variability in Older Chinese Individuals with Depression.International journal of environmental research and public health · 2018
    Trial
  11. Article
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  14. Review
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  18. The Safety of Baduanjin Exercise: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
  19. Mind-Body Health Benefits of Traditional ChineseEvidence-based complementary and alternative medicine : eCAM · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Jessie S M Chan
Ang Li
Siu-Man Ng
Rainbow T H Ho
Aimin Xu
Tzy-Jyun Yao
Xiao-Min Wang
Kwok-Fai So
Cecilia L W Chan
University of Hong Kong · HKChinese University of Hong Kong · CNHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our recent study demonstrates that adiponectin signaling plays a significant role in mediating physical exercise-exerted effects on hippocampal neurogenesis and antidepression in mice. Whether the findings can be translated to humans remains unknown. This study aimed to investigate the effects of Baduanjin Qigong exercise on adiponectin and to evaluate whether adiponectin is involved in the antidepressive effects of Qigong exercise on chronic fatigue syndrome (CFS)-like illness. This is a randomized, waitlist-controlled trial. One hundred eight female participants were randomly assigned to either Qigong exercise or waitlist groups. Sixteen 1.5-h Qigong lessons were conducted. Outcome measures were taken at three time points. Baseline adiponectin levels were negatively associated with body weight, body mass index, waist circumference, hip circumference, and waist/hip ratio in women with CFS-like illness. Compared with the waitlist control, Qigong exercise significantly reduced anxiety and depression symptoms and significantly raised plasma adiponectin levels (median = 0.8 vs. -0.1, p < 0.05). More interestingly, increases in adiponectin levels following Qigong exercise were associated with decreases in depression scores for the Qigong group (r = -0.38, p = 0.04). Moreover, adjusted linear regression analysis further identified Qigong exercise and change in adiponectin levels as the significant factors accounting for reduction of depression symptoms. Baduanjin Qigong significantly increased adiponectin levels in females with CFS-like illness. Decreases in depression symptoms were associated with increases in adiponectin levels following Qigong exercise, indicating that the potential contribution of adiponectin to Qigong exercise elicited antidepressive effects in human subjects.

Indexed as

QigongAdiponectinAdultBody Mass IndexDepressionFatigue Syndrome, ChronicFemaleHumansMiddle AgedQuality of LifeWaist CircumferenceWaist-Hip RatioAdiponectin

Identifiers

PMID27938498
PMCPMC5657703
OpenAlexW2585566530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.