Evidence map›Paper›PMID 27936604›Full record

ArticleAnalytical chemistry2017

Microscale Measurements of Michaelis-Menten Constants of Neuraminidase with Nanogel Capillary Electrophoresis for the Determination of the Sialic Acid Linkage.

Srikanth Gattu, Cassandra L Crihfield, Lisa A Holland

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Investigation of experimental factors in in-capillary continuous enzyme assay to obtain plateau response by electrophoretically mediated microanalysis.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Srikanth GattuC. Eugene Bennett Department of Chemistry, West Virginia University , Morgantown, West Virginia 26506, United States.
Cassandra L CrihfieldC. Eugene Bennett Department of Chemistry, West Virginia University , Morgantown, West Virginia 26506, United States.
Lisa A HollandC. Eugene Bennett Department of Chemistry, West Virginia University , Morgantown, West Virginia 26506, United States.ORCID 0000-0002-7534-6810
West Virginia University · US

Funding

Phospholipid Microscale Glycan Sequencing: Linking Structure to Antibody FunctionR01GM114330 · NIGMS · WEST VIRGINIA UNIVERSITY · PI HOLLAND, LISA A · 2015 to 2019
$1.4M
NIGMS NIH HHS R01 GM114330
6 · The paper itself

Abstract

Phospholipid nanogels enhance the stability and performance of the exoglycosidase enzyme neuraminidase and are used to create a fixed zone of enzyme within a capillary. With nanogels, there is no need to covalently immobilize the enzyme, as it is physically constrained. This enables rapid quantification of Michaelis-Menten constants (K

Indexed as

NanoparticlesClostridium perfringensElectrophoresis, CapillaryGelsN-Acetylneuraminic AcidNeuraminidaseGelsN-Acetylneuraminic AcidNeuraminidase

Identifiers

PMID27936604
PMCPMC5214287
OpenAlexW2560910767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.