Evidence map›Paper›PMID 27936462›Full record

ArticleVirology2017

Sinu virus, a novel and divergent orthomyxovirus related to members of the genus Thogotovirus isolated from mosquitoes in Colombia.

María Angélica Contreras-Gutiérrez, Marcio R T Nunes, Hilda Guzman, Sandra Uribe, Juan David Suaza Vasco, Jedson F Cardoso, Vsevolod L Popov, Steven G Widen, Thomas G Wood, Nikos Vasilakis and 1 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
8.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 31 citations in OpenAlex.

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  5. Characterisation of the virome ofThe Journal of general virology · 2025
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  8. Exploring viral infections in honey bee colonies: insights from a metagenomic study in southern Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

María Angélica Contreras-GutiérrezPrograma de Estudio y Control de Enfermedades Tropicales - PECET - SIUSde de Investigación Universitaria - Universidad de Antioquia, Medellín, Colombia; Grupo de Investigación en Sistemática Molecular-GSM, Facultad de Ciencias, Universidad Nacional de Colombia, sede Medellín, Medellín, Colombia.
Marcio R T NunesCenter for Technological Innovation, Evandro Chagas Institute, Ministry of Health, Ananindeua, Para, Brazil.
Hilda GuzmanDepartment of Pathology, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA.
Sandra UribeGrupo de Investigación en Sistemática Molecular-GSM, Facultad de Ciencias, Universidad Nacional de Colombia, sede Medellín, Medellín, Colombia.
Juan David Suaza VascoPrograma de Estudio y Control de Enfermedades Tropicales - PECET - SIUSde de Investigación Universitaria - Universidad de Antioquia, Medellín, Colombia; Grupo de Investigación en Sistemática Molecular-GSM, Facultad de Ciencias, Universidad Nacional de Colombia, sede Medellín, Medellín, Colombia.
Jedson F CardosoCenter for Technological Innovation, Evandro Chagas Institute, Ministry of Health, Ananindeua, Para, Brazil.
Vsevolod L PopovDepartment of Pathology, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA.
Steven G WidenDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
Thomas G WoodDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
Nikos VasilakisDepartment of Pathology, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA. Electronic address: nivasila@utmb.edu.
Robert B TeshDepartment of Pathology, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, USA. Electronic address: rtesh@utmb.edu.
The University of Texas Medical Branch at Galveston · USUniversidad de Antioquia · COMinistério da Saúde · BRUniversidad Nacional de Colombia · CO

Funding

World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)R24AI120942 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WEAVER, SCOTT C · 2016 to 2024
$8.5M
NIAID NIH HHS R24 AI120942
6 · The paper itself

Abstract

The genome and structural organization of a novel insect-specific orthomyxovirus, designated Sinu virus, is described. Sinu virus (SINUV) was isolated in cultures of C6/36 cells from a pool of mosquitoes collected in northwestern Colombia. The virus has six negative-sense ssRNA segments. Genetic analysis of each segment demonstrated the presence of six distinct ORFs encoding the following genes: PB2 (Segment 1), PB1, (Segment 2), PA protein (Segment 3), envelope GP gene (Segment 4), the NP (Segment 5), and M-like gene (Segment 6). Phylogenetically, SINUV appears to be most closed related to viruses in the genus Thogotovirus.

Indexed as

Evolution, MolecularAmino Acid SequenceAnimalsColombiaCulicidaeGenome, ViralModels, MolecularMolecular Sequence DataOrthomyxoviridaePhylogenyThogotovirusViral ProteinsViral ProteinsInsect-specific virusesOrthomyxoviridaeSinu virusThogotovirus genus

Identifiers

PMID27936462
PMCPMC5201441
OpenAlexW2559783012

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.