ReviewAnnals of the New York Academy of Sciences2017
Utility of preclinical drug versus food choice procedures to evaluate candidate medications for methamphetamine use disorder.
Review in Annals of the New York Academy of Sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Preclinical Evaluation of Dual NOP/Mu Partial Agonists for Methamphetamine Use Disorder.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Mitragynine reduces methamphetamine self-administration in rats without disrupting food-maintained responding.Psychopharmacology · 2026Article
- Ethanol self-administration reduced the efficacy of a behavioral intervention to decrease cocaine choice in socially housed male and female monkeys.Drug and alcohol dependence · 2025Article
- Lorcaserin maintenance fails to attenuate heroin vs. food choice in rhesus monkeys.Drug and alcohol dependence · 2020Article
- Nonhuman animal models of substance use disorders: Translational value and utility to basic science.Drug and alcohol dependence · 2020Review
- Conjugate vaccine produces long-lasting attenuation of fentanyl vs. food choice and blocks expression of opioid withdrawal-induced increases in fentanyl choice in rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Article
- Moderate-Intensity Aerobic Exercise Restores Appetite and Prefrontal Brain Activity to Images of Food Among Persons Dependent on Methamphetamine: A Functional Near-Infrared Spectroscopy Study.Frontiers in human neuroscience · 2019Article
- Effects of alcohol dependence on discrete choice between alcohol and saccharin.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Article
- Varenicline and GZ-793A differentially decrease methamphetamine self-administration under a multiple schedule of reinforcement in rats.Behavioural pharmacology · 2018Article
- Utility of Nonhuman Primates in Substance Use Disorders Research.ILAR journal · 2017Review
- Insights from Preclinical Choice Models on Treating Drug Addiction.Trends in pharmacological sciences · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Substance use disorders are diagnosed as a manifestation of inappropriate behavioral allocation toward abused drugs and away from other behaviors maintained by more adaptive nondrug reinforcers (e.g., money and social relationships). Substance use disorder treatment goals include not only decreasing drug-maintained behavior but also promoting behavioral reallocation toward these socially adaptive alternative reinforcers. Preclinical drug self-administration procedures that offer concurrent access to both drug and nondrug reinforcers provide a translationally relevant dependent measure of behavioral allocation that may be useful for candidate medication evaluation. In contrast to other abused drugs, such as heroin or cocaine, preclinical methamphetamine versus food choice procedures have been a more recent development. We hypothesize that preclinical to clinical translatability would be improved by the evaluation of repeated pharmacological treatment effects on methamphetamine self-administration under a methamphetamine versus food choice procedure. In support of this hypothesis, a literature review suggests strong concordance between preclinical pharmacological treatment effects on methamphetamine versus food choice in nonhuman primates and clinical medication treatment effects on methamphetamine self-administration in human laboratory studies or methamphetamine abuse metrics in clinical trials. In conclusion, this literature suggests preclinical methamphetamine versus food choice procedures may be useful in developing innovative pharmacotherapies for methamphetamine use disorder.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.