Evidence map›Paper›PMID 27936097›Full record

ArticlePloS one2016

PeTMbase: A Database of Plant Endogenous Target Mimics (eTMs).

Gökhan Karakülah, Kuaybe Yücebilgili Kurtoğlu, Turgay Unver

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
17.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 61 citations in OpenAlex.

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  5. Artificial miRNAs and target-mimics as potential tools for crop improvement.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
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  15. Interactions and links among the noncoding RNAs in plants under stresses.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gökhan Karakülahİzmir International Biomedicine and Genome Institute (iBG-izmir), Dokuz Eylül University, İnciraltı, İzmir, Turkey.
Kuaybe Yücebilgili KurtoğluDepartment of Molecular Biology and Genetics, İstanbul Medeniyet University, İstanbul, Turkey.
Turgay Unverİzmir International Biomedicine and Genome Institute (iBG-izmir), Dokuz Eylül University, İnciraltı, İzmir, Turkey.ORCID http://orcid.org/0000-0001-6760-443X
Izmir University · TRIstanbul Medeniyet University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNA) are small endogenous RNA molecules, which regulate target gene expression at post-transcriptional level. Besides, miRNA activity can be controlled by a newly discovered regulatory mechanism called endogenous target mimicry (eTM). In target mimicry, eTMs bind to the corresponding miRNAs to block the binding of specific transcript leading to increase mRNA expression. Thus, miRNA-eTM-target-mRNA regulation modules involving a wide range of biological processes; an increasing need for a comprehensive eTM database arose. Except miRSponge with limited number of Arabidopsis eTM data no available database and/or repository was developed and released for plant eTMs yet. Here, we present an online plant eTM database, called PeTMbase (http://petmbase.org), with a highly efficient search tool. To establish the repository a number of identified eTMs was obtained utilizing from high-throughput RNA-sequencing data of 11 plant species. Each transcriptome libraries is first mapped to corresponding plant genome, then long non-coding RNA (lncRNA) transcripts are characterized. Furthermore, additional lncRNAs retrieved from GREENC and PNRD were incorporated into the lncRNA catalog. Then, utilizing the lncRNA and miRNA sources a total of 2,728 eTMs were successfully predicted. Our regularly updated database, PeTMbase, provides high quality information regarding miRNA:eTM modules and will aid functional genomics studies particularly, on miRNA regulatory networks.

Indexed as

ArabidopsisBase SequenceDatabases, GeneticGene Expression Regulation, PlantGene Regulatory NetworksGenome, PlantHigh-Throughput Nucleotide SequencingMicroRNAsPlantsRNA, Long NoncodingRNA, MessengerRNA, PlantTranscriptomeMicroRNAsRNA, Long NoncodingRNA, MessengerRNA, Plant

Identifiers

PMID27936097
PMCPMC5148581
OpenAlexW2560090610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.