ArticlePloS one2016
Baroreflex Sensitivity Predicts Short-Term Outcome of Postural Tachycardia Syndrome in Children.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guidelines for the diagnosis and treatment of neurally mediated syncope in children and adolescents (revised 2024).World journal of pediatrics : WJP · 2024Guideline
- Treatment of Headache in Children and Adolescents with POTS.Current pain and headache reports · 2026Review
- Anxiety and depression moods is involved in the pathogenesis of postural tachycardia syndrome.IBRO neuroscience reports · 2025Article
- Pediatric postural orthostatic tachycardia syndrome: From mechanisms to individualized management.Pediatric discovery · 2024Review
- Predicting Therapeutic Efficacy of Pharmacological Treatments in Children with Postural Orthostatic Tachycardia Syndrome: A Mini-Review.Children (Basel, Switzerland) · 2023Review
- Biomarkers and Hemodynamic Parameters in the Diagnosis and Treatment of Children with Postural Tachycardia Syndrome and Vasovagal Syncope.International journal of environmental research and public health · 2022Review
- Arterial Baroreceptor Physiology: Differences Between Normal Subjects and Pediatric Patients with Postural Tachycardia and Neurocardiogenic Syncope.Pediatric cardiology · 2022Article
- Predictive Value of Heart Rate and Blood Pressure on the Prognosis of Postural Tachycardia Syndrome in Children.Frontiers in pediatrics · 2022Article
- Baroreflex sensitivity predicts therapeutic effects of metoprolol on pediatric postural orthostatic tachycardia syndrome.Frontiers in cardiovascular medicine · 2022Article
- Interplay between baroreflex sensitivity, obesity and related cardiometabolic risk factors (Review).Experimental and therapeutic medicine · 2022Review
- Prognostic Value of Biomarkers in Children and Adolescents With Orthostatic Intolerance.Frontiers in pediatrics · 2021Review
- Pathophysiology and Individualized Management of Vasovagal Syncope and Postural Tachycardia Syndrome in Children and Adolescents: An Update.Neuroscience bulletin · 2020Review
- Homocysteine: Its Possible Emerging Role in At-Risk Population Groups.International journal of molecular sciences · 2020Review
- Postural Tachycardia Syndrome in Children and Adolescents: Pathophysiology and Clinical Management.Frontiers in pediatrics · 2020Review
- Long-Term Outcomes of Children and Adolescents With Postural Tachycardia Syndrome After Conventional Treatment.Frontiers in pediatrics · 2019Article
- Beyond HRV: attractor reconstruction using the entire cardiovascular waveform data for novel feature extraction.Physiological measurement · 2018Article
- Plasma Homocysteine Level in Children With Postural Tachycardia Syndrome.Frontiers in pediatrics · 2018Article
- Pediatric Cardiology: Advances Over the Past 2 Years and Future Prospects.Chinese medical journal · 2017Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe study was designed to examine if baroreflex sensitivity (BRS) could predict the short-term outcome of postural tachycardia syndrome (POTS) in children.
methodsSeventy-seven children subjects were included in the study. Among them, 45 children were in the POTS group and another 32 healthy children were in the control group. A ninety-day clinical follow-up was conducted and the symptom score before and after the follow-up was calculated for POTS patients by using POTS score system. Hemodynamics and continuous BRS monitoring were recorded by Finapres Medical System-FMS (FinometerPRO, FMS Company, Netherlands). According to the symptom score change during follow-up period, POTS patients were further divided into subgroup A (n = 24) with symptom score decreased by at least two points and subgroup B (n = 21) with symptom score decreased by less than two points. The predictive value of BRS in the short-term outcome of POTS in children was analyzed using receiver-operating characteristic (ROC) curve.
resultsBRS of POTS children was significantly higher than that of the healthy children (18.76±9.96 ms/mmHg vs 10±5.42 ms/mmHg, P<0.01). It was higher in subgroup B than that of subgroup A (24.7±9.9 ms/mmHg vs 13.5±6.6 ms/mmHg, P <0.01). BRS was positively correlated with HR change in POTS Group (r = 0.304, P <0.05). Area under curve (AUC) was 0.855 (95% of confidence interval 0.735-0.975), and BRS of 17.01 ms/mmHg as a cut-off value yielded the predictive sensitivity of 85.7% and specificity of 87.5%.
conclusionsBRS is a useful index to predict the short-term outcome of POTS in children.
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Registered trials
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