Trial reportThe Journal of clinical endocrinology and metabolism2017
Effect of Physical Activity and/or Healthy Eating on GDM Risk: The DALI Lifestyle Study.
Trial report in The Journal of clinical endocrinology and metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 13 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
127 citing papers in PubMed, 13 syntheses or guidelines pooled it, 222 citations in OpenAlex.
- Behavior change techniques in pregnancy dietary interventions: a systematic review through the lens of the COM-B model.BMC pregnancy and childbirth · 2025Pooled it
- Systematic review of interventions in early pregnancy among pregnant individuals at risk for hyperglycemia.American journal of obstetrics & gynecology MFM · 2025Pooled it
- Effective dietary interventions during pregnancy: a systematic review and meta-analysis of behavior change techniques to promote healthy eating.BMC pregnancy and childbirth · 2025Pooled it
- A systematic review and meta-analysis of exercise-based intervention to prevent gestational diabetes in women with overweight or obesity.BMC pregnancy and childbirth · 2025Pooled it
- Effects of mHealth-Based Lifestyle Interventions on Gestational Diabetes Mellitus in Pregnant Women With Overweight and Obesity: Systematic Review and Meta-Analysis.JMIR mHealth and uHealth · 2024Pooled it
- Comprehensive management of gestational diabetes mellitus: practical efficacy of exercise therapy and sustained intervention strategies.Frontiers in endocrinology · 2024Pooled it
- Key Components of Antenatal Lifestyle Interventions to Optimize Gestational Weight Gain: Secondary Analysis of a Systematic Review.JAMA network open · 2023Pooled it
- The effect of motivational interviewing and/or cognitive behaviour therapy techniques on gestational weight gain - a systematic review and meta-analysis.BMC public health · 2023Pooled it
- Exercise during pregnancy for preventing gestational diabetes mellitus and hypertensive disorders: An umbrella review of randomised controlled trials and an updated meta-analysis.BJOG : an international journal of obstetrics and gynaecology · 2023Pooled it
- Implementation of Antenatal Lifestyle Interventions Into Routine Care: Secondary Analysis of a Systematic Review.JAMA network open · 2022Pooled it
- Pooled it
- Effect of diet and physical activity based interventions in pregnancy on gestational weight gain and pregnancy outcomes: meta-analysis of individual participant data from randomised trials.BMJ (Clinical research ed.) · 2017Pooled it
- Interventions to increase self-reported physical activity during pregnancy: A systematic review.Women's health (London, England)Pooled it
- Vitamin D Deficiency During Pregnancy Is Associated With Greater LDL-C Increase, Elevated β-Hydroxybutyrate and Altered Neonatal Metabolic Markers-A Secondary, Pooled Analysis of the Randomized, Controlled Vitamin D and Lifestyle for Gestational Diabetes Prevention Trial (DALI).Endocrinology, diabetes & metabolism · 2026Trial
- [A randomized controlled trial of weight management based on mobile health techno-logy among overweight or obese pregnant women].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025Trial
- Effect of a physical activity and healthy eating lifestyle intervention in pregnancy on fetal growth trajectories: The DALI randomised controlled trial.Pediatric obesity · 2025Trial
- Nutritional education on health beliefs, metabolic profiles, and quality of life among high-risk pregnant women for gestational diabetes mellitus: a randomized controlled trial.Scientific reports · 2024Trial
- REduced-Carbohydrate intervention for managing Obesity and Reduction of gestational Diabetes (RECORD): A randomized controlled feasibility trial.Diabetes, obesity & metabolism · 2024Trial
- Development and feasibility of a theory-guided and evidence-based physical activity intervention in pregnant women with high risk for gestational diabetes mellitus: a pilot clinical trial.BMC pregnancy and childbirth · 2023Trial
- Acceptability and feasibility of a planned preconception weight loss intervention in women with long-acting reversible contraception: the Plan-it mixed-methods study.Health technology assessment (Winchester, England) · 2023Trial
67 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 15 institutions in 10 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextLifestyle approaches for preventing gestational diabetes mellitus (GDM) have produced mixed results.
objectiveThe aim of the present study was to compare the effectiveness of 3 lifestyle interventions [healthy eating (HE), physical activity (PA), and both HE and PA (HE+PA)] with usual care (UC) in reducing GDM risk.
designThe present study was a multicenter randomized controlled trial conducted from 2012 to 2014 [the DALI (vitamin D and lifestyle intervention for GDM prevention) lifestyle study].
settingThe study occurred at antenatal clinics across 11 centers in 9 European countries. PATIENTS: Consecutive pregnant women at <20 weeks of gestation with a body mass index (BMI) of ≥29 kg/m2 and without GDM using the International Association of Diabetes and Pregnancy Study Group criteria (n = 436). For the intervention, women were randomized, stratified by site, to UC, HE, PA, or HE+PA. The women received 5 face-to-face and ≤4 telephone coaching sessions using the principles of motivational interviewing. A gestational weight gain (GWG) <5 kg was targeted. The coaches received standardized training and an intervention toolkit tailored to their culture and language.
main outcome measuresThe endpoints were the GWG at 35 to 37 weeks and the fasting glucose and insulin sensitivity [homeostasis model assessment insulin resistance (HOMA-IR)] at 24 to 28 weeks.
resultsWe randomized 108 women to HE+PA, 113 to HE, 110 to PA, and 105 to UC. In the HE+PA group, but not HE or PA alone, women achieved substantially less GWG than did the controls (UC) by 35 to 37 weeks (-2.02; 95% confidence interval, -3.58 to -0.46 kg). Despite this reduction, no improvements were seen in fasting or postload glucose levels, insulin concentrations, or HOMA-IR. The birthweights and large and small for gestational age rates were similar.
conclusionsThe combined HE+PA intervention was able to limit GWG but did not reduce fasting glycemia. Thus, lifestyle changes alone are unlikely to prevent GDM among women with a BMI of ≥29 kg/m2.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.