Evidence map›Paper›PMID 27935716›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2016

Fluctuation Spectroscopy Analysis of Glucose Capped Gold Nanoparticles.

F Porcaro, Y Miao, R Kota, J B Haun, G Polzonetti, C Battocchio, E Gratton

Abstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Functional endoscopy techniques for tracking stem cell fate.Quantitative imaging in medicine and surgery · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

F PorcaroRoma Tre University , Department of Sciences, Via della Vasca Navale 79, 00146 - Rome, Italy.ORCID 0000-0001-6506-1398
Y Miao
R Kota
J B Haun
G PolzonettiRoma Tre University , Department of Sciences, Via della Vasca Navale 79, 00146 - Rome, Italy.
C BattocchioRoma Tre University , Department of Sciences, Via della Vasca Navale 79, 00146 - Rome, Italy.
E Gratton

Funding

TRD4: Phasor analysisP41GM103540 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GRATTON, ENRICO · 2012 to 2020
$12.5M
NIGMS NIH HHS P41 GM103540
6 · The paper itself

Abstract

In this work, we report the synthesis and biophysical studies carried out on a new kind of biocompatible and very stable gold nanoparticle (GNP) stabilized with glucose through a PEG linker (AuNP-PEG-Glu). The synthetic path was optimized to obtain nanoparticles of controlled sizes. ζ-potential and dynamic light scattering measurements allowed assessment of the nanodimension, dispersity, surface charge, and stability of our GNPs. Confocal microscopy demonstrated qualitatively that glucose molecules are successfully bonded to GNP surfaces. For our study, we selected nanoparticles with diameter in a range that maximizes the internalization efficiency in cells (40 nm). A detailed investigation about the biophysical proprieties of AuNP-PEG-Glu was carried out by means of fluorescence correlation spectroscopy (FCS) and orbital tracking techniques. This work gives new insights about the uptake mechanism of gold nanoparticles capped with glucose molecules.

Indexed as

GoldBiocompatible MaterialsDynamic Light ScatteringGenes, ReporterGlucoseGlucose Transporter Type 1Green Fluorescent ProteinsHeLa CellsHumansMetal NanoparticlesSpectrum AnalysisTransfectionBiocompatible MaterialsGlucoseGlucose Transporter Type 1GoldGreen Fluorescent Proteins

Identifiers

PMID27935716
PMCPMC5470844

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.