ArticleTropical medicine & international health : TM & IH2017
Point-of-care assessment of C-reactive protein and white blood cell count to identify bacterial aetiologies in malaria-negative paediatric fevers in Tanzania.
Article in Tropical medicine & international health : TM & IH, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Diagnostic value of biomarkers for paediatric urinary tract infections in primary care: systematic review and meta-analysis.BMC family practice · 2021Pooled it
- Usefulness of C-Reactive Protein and Other Host BioMarker Point-of-Care Tests in the Assessment of Non-Malarial Acute Febrile Illnesses: A Systematic Review with Meta-Analysis.The American journal of tropical medicine and hygiene · 2020Pooled it
- Trial
- Linear correlation between white blood cell counts and the progression and prognosis of acute kidney injury.The Journal of international medical research · 2025Trial
- The social role of C-reactive protein point-of-care testing to guide antibiotic prescription in Northern Thailand.Social science & medicine (1982) · 2018Trial
- Article
- C-Reactive Protein for the Early Assessment of Non-Malarial Febrile Patients: A Retrospective Diagnostic Study.Diagnostics (Basel, Switzerland) · 2021Article
- Tanzanian primary healthcare workers' experiences of antibiotic prescription and understanding of antibiotic resistance in common childhood infections: a qualitative phenomenographic study.Antimicrobial resistance and infection control · 2021Article
- Point-of-Care Biomarkers to Guide Antibiotic Prescription for Acute Febrile Illness in Sub-Saharan Africa: Promises and Caveats.Open forum infectious diseases · 2020Review
- Incidence and Risk Factors for Severe Pneumonia in Children Hospitalized with Pneumonia in Ujjain, India.International journal of environmental research and public health · 2020Article
- The good and the bad: using C reactive protein to distinguish bacterial from non-bacterial infection among febrile patients in low-resource settings.BMJ global health · 2020Review
- Sensitivity of C-reactive protein for the identification of patients with laboratory-confirmed bacterial infections in northern Tanzania.Tropical medicine & international health : TM & IH · 2020Article
- High Circulation of Malaria and Low Prevalence of Bacteremia in Febrile and Afebrile Children in Northeastern Gabon.The American journal of tropical medicine and hygiene · 2020Article
- Performance of prediction rules and guidelines in detecting serious bacterial infections among Tanzanian febrile children.BMC infectious diseases · 2019Article
- Article
- A Comparison of Patients' Local Conceptions of Illness and Medicines in the Context of C-Reactive Protein Biomarker Testing in Chiang Rai and Yangon.The American journal of tropical medicine and hygiene · 2018Article
Corrections and comments
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Authors and funding
6 authors at 6 institutions in 3 countries.
Funding
Abstract
objectiveTo assess the role of point-of-care (PoC) assessment of C-reactive protein (CRP) and white blood cell (WBC) count to identify bacterial illness in Tanzanian children with non-severe non-malarial fever.
methodsFrom the outpatient department of a district hospital in Tanzania, 428 patients between 3 months and 5 years of age who presented with fever and a negative malaria test were enrolled. All had a physical examination and bacterial cultures from blood and urine. Haemoglobin, CRP and WBC were measured by PoC devices.
resultsPositive blood cultures were detected in 6/428 (1.4%) children and urine cultures were positive in 24/401 (6.0%). Mean WBC was similar in children with or without bacterial illness (14.0 × 10
conclusionWBC and CRP levels had limited value in identifying children with bacterial infections. The positive predictive values for both tests were too low to be used as single tools for treatment decisions.
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Registered trials
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