Evidence map›Paper›PMID 27935612›Full record

ArticleBiomaterials science2016

Fabricating polyacrylamide microbeads by inverse emulsification to mimic the size and elasticity of living cells.

Nicholas R Labriola, Edith Mathiowitz, Eric M Darling

Abstract read
In one paragraph

Article in Biomaterials science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicholas R LabriolaCenter for Biomedical Engineering, Brown University, Providence, RI 02912, USA.
Edith MathiowitzDepartment of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, RI 02912, USA.
Eric M DarlingDepartment of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, RI 02912, USA and School of Engineering and Department of Orthopaedics, Brown University, Providence, RI 02906, USA. Eric_Darling@brown.edu.ORCID http://orcid.org/0000-0002-3932-8623

Funding

COBRE for Skeletal Health and RepairP20GM104937 · NIGMS · RHODE ISLAND HOSPITAL · PI CHEN, QIAN · 2012 to 2016
$10.8M
High-yield, lineage-specific enrichment of living mesenchymal stem cellsR01AR063642 · NIAMS · BROWN UNIVERSITY · PI DARLING, ERIC M · 2013 to 2018
$1.8M
NIAMS NIH HHS R01 AR063642NIGMS NIH HHS P20 GM104937
6 · The paper itself

Abstract

Inverse emulsification was used to fabricate polyacrylamide (PAAm) microbeads with size and elastic properties similar to typical, mammalian cells. These biomimicking microbeads could be fluorescently stained and functionalized with a collagen type-I coating, post-polymerization, for tracking bead locations and promoting cell recognition/binding, respectively. By occupying a previously unfilled range of sizes and mechanical properties, these microbeads may find unique use in both biomedical and materials applications.

Indexed as

MicrospheresAcrylic ResinsCellsElasticityEmulsionsParticle SizePolyacrylamidesAcrylic ResinsEmulsionsPolyacrylamides

Identifiers

PMID27935612
PMCPMC5201106

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.