ArticleThe ISME journal2017
Identification of the fitness determinants of budding yeast on a natural substrate.
Article in The ISME journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Maple Syrup and Bacillus velezensis based Supplement: in Vivo Study of the Impact on Growth Performance, Microbiota Composition, and Metabolic Activity in Weaned Piglets.Current microbiology · 2025Article
- Systematic Evaluation of Biotic and Abiotic Factors in Antifungal Microorganism Screening.Microorganisms · 2024Article
- Natural trait variation across Saccharomycotina species.FEMS yeast research · 2024Review
- The Physicochemical Characterization and In Vitro Digestibility of Maple Sugar Sand and Downgraded Maple Syrups.Foods (Basel, Switzerland) · 2023Article
- Mitochondrial-nuclear coadaptation revealed through mtDNA replacements in Saccharomyces cerevisiae.BMC evolutionary biology · 2020Article
- A continuously changing selective context on microbial communities associated with fish, from egg to fork.Evolutionary applications · 2020Article
- Competition experiments in a soil microcosm reveal the impact of genetic and biotic factors on natural yeast populations.The ISME journal · 2020Article
- Hybridization is a recurrent evolutionary stimulus in wild yeast speciation.Nature communications · 2019Article
- Comparative Genomics BetweenFrontiers in genetics · 2019Article
- A systems biology approach to explore the impact of maple tree dormancy release on sap variation and maple syrup quality.Scientific reports · 2018Article
- Persistence of Resident and Transplanted Genotypes of the Undomesticated Yeast Saccharomyces paradoxus in Forest Soil.mSphere · 2018Article
- Evolutionary biology through the lens of budding yeast comparative genomics.Nature reviews. Genetics · 2017Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The budding yeasts are prime models in genomics and cell biology, but the ecological factors that determine their success in non-human-associated habitats is poorly understood. In North America Saccharomyces yeasts are present on the bark of deciduous trees, where they feed on bark and sap exudates. In the North East, Saccharomyces paradoxus is found on maples, which makes maple sap a natural substrate for this species. We measured growth rates of S. paradoxus natural isolates on maple sap and found variation along a geographical gradient not explained by the inherent variation observed under optimal laboratory conditions. We used a functional genomic screen to reveal the ecologically relevant genes and conditions required for optimal growth in this substrate. We found that the allantoin degradation pathway is required for optimal growth in maple sap, in particular genes necessary for allantoate utilization, which we demonstrate is the major nitrogen source available to yeast in this environment. Growth with allantoin or allantoate as the sole nitrogen source recapitulated the variation in growth rates in maple sap among strains. We also show that two lineages of S. paradoxus display different life-history traits on allantoin and allantoate media, highlighting the ecological relevance of this pathway.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.