ArticleThe ISME journal2017
Use of plankton-derived vitamin B1 precursors, especially thiazole-related precursor, by key marine picoeukaryotic phytoplankton.
Article in The ISME journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 64 citations in OpenAlex.
- Vesicle-associated exudates fromApplied and environmental microbiology · 2026Article
- Biological and genomic resources for the cosmopolitan phytoplankton Bathycoccus: insights into genetic diversity and function of outlier chromosomes.The Plant journal : for cell and molecular biology · 2026Article
- Functional complementarity between vitamin B1 and B12 metabolisms shapes seasonal marine microbial communities.The ISME journal · 2026Article
- Pronounced seasonal dynamics in transcription of vitamin B1 acquisition strategies diverge among Baltic Sea bacterioplankton.Environmental microbiome · 2025Article
- Phylogenomics Untangles the Metabolic Potential of Picochlorum tauri, a New Picoalgal Species Causing a Winter Bloom in the Mediterranean Thau Lagoon.Environmental microbiology · 2025Article
- Vitamin auxotrophies shape microbial community assembly on model marine particles.The ISME journal · 2025Article
- Dark ocean archaeal and bacterial chemoautotrophs drive vitamin B1 production in oxygen minimum zones.ISME communications · 2025Article
- Bacimethrin, an allelopathic vitamin B1 antagonist, is linked with microbial gene expression patterns in a hypereutrophic watershed.PloS one · 2025Article
- Connecting thiamine availability to the microbial community composition in Chinook salmon spawning habitats of the Sacramento River basin.Applied and environmental microbiology · 2024Article
- Thiamin (vitamin B1, thiamine) transfer in the aquatic food web from lower to higher trophic levels.PloS one · 2024Article
- New chemical and microbial perspectives on vitamin B1 and vitamer dynamics of a coastal system.ISME communications · 2024Article
- Article
- A Salvaging Strategy Enables Stable Metabolite Provisioning among Free-Living Bacteria.mSystems · 2022Article
- Exchange of Vitamin BJournal of bacteriology · 2022Article
- Shared features and reciprocal complementation of the Chlamydomonas and Arabidopsis microbiota.Nature communications · 2022Article
- Community Interaction Co-limitation: Nutrient Limitation in a Marine Microbial Community Context.Frontiers in microbiology · 2022Article
- Features of the Opportunistic Behaviour of the Marine BacteriumMicroorganisms · 2021Article
- Phytoplankton consortia as a blueprint for mutually beneficial eukaryote-bacteria ecosystems based on the biocoenosis of Botryococcus consortia.Scientific reports · 2021Article
- Auxotrophic interactions: a stabilizing attribute of aquatic microbial communities?FEMS microbiology ecology · 2020Article
- Rapid microbial diversification of dissolved organic matter in oceanic surface waters leads to carbon sequestration.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several cosmopolitan marine picoeukaryotic phytoplankton are B1 auxotrophs requiring exogenous vitamin B1 or precursor to survive. From genomic evidence, representatives of picoeukaryotic phytoplankton (Ostreococcus and Micromonas spp.) were predicted to use known thiazole and pyrimidine B1 precursors to meet their B1 demands, however, recent culture-based experiments could not confirm this assumption. We hypothesized these phytoplankton strains could grow on precursors alone, but required a thiazole-related precursor other the well-known and extensively tested 4-methyl-5-thiazoleethanol. This hypothesis was tested using bioassays and co-cultures of picoeukaryotic phytoplankton and bacteria. We found that specific B1-synthesizing proteobacteria and phytoplankton are sources of a yet-to-be chemically identified thiazole-related precursor(s) that, along with pyrimidine B1 precursor 4-amino-5-hydroxymethyl-2-methylpyrimidine, can support growth of Ostreococcus spp. (also Micromonas spp.) without B1. We additionally found that the B1-synthesizing plankton do not require contact with picoeukaryotic phytoplankton cells to produce thiazole-related precursor(s). Experiments with wild-type and genetically engineered Ostreococcus lines revealed that the thiazole kinase, ThiM, is required for growth on precursors, and that thiazole-related precursor(s) accumulate to appreciable levels in the euphotic ocean. Overall, our results point to thiazole-related B1 precursors as important micronutrients promoting the survival of abundant phytoplankton influencing surface ocean production and biogeochemical cycling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.