Observational studyThe American journal of clinical nutrition2016
The role of obesity in the relation between total water intake and urine osmolality in US adults, 2009-2012.
Observational study in The American journal of clinical nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 60 citations in OpenAlex.
- Variation in urine osmolality throughout pregnancy: a longitudinal, randomized-control trial among women with overweight and obesity.European journal of nutrition · 2022Trial
- Water intake, hydration, and weight management: the glass is half-full!Physiology & behavior · 2025Review
- Article
- Ad libitum dehydration is associated with poorer performance on a sustained attention task but not other measures of cognitive performance among middle-to-older aged community-dwelling adults: A short-term longitudinal study.American journal of human biology : the official journal of the Human Biology Council · 2024Article
- Detection of low urine output by measuring urinary biomarkers.BMC nutrition · 2024Article
- Hydration status in adults with metabolic disorders in relation to socioeconomic, lifestyle and health factors.PloS one · 2024Article
- Identifying the main predictors of urine output in autosomal-dominant polycystic kidney disease (ADPKD) patients taking tolvaptan.International urology and nephrology · 2023Article
- Water intake, hydration status and 2-year changes in cognitive performance: a prospective cohort study.BMC medicine · 2023Article
- THIRSTY FOR FRUCTOSE: Arginine Vasopressin, Fructose, and the Pathogenesis of Metabolic and Renal Disease.Frontiers in cardiovascular medicine · 2022Review
- Water Intake and Markers of Hydration Are Related to Cardiometabolic Risk Biomarkers in Community-Dwelling Older Adults: A Cross-Sectional Analysis.The Journal of nutrition · 2021Article
- Hydration status, body composition, and anxiety status in aeronautical military personnel from Spain: a cross-sectional study.Military Medical Research · 2021Article
- Hydration in relation to water insecurity, heat index, and lactation status in two small-scale populations in hot-humid and hot-arid environments.American journal of human biology : the official journal of the Human Biology Council · 2021Article
- Cognitive performance in relation to hydration status and water intake among older adults, NHANES 2011-2014.European journal of nutrition · 2020Article
- High-fat diet alters fluid intake without reducing sensitivity to glucagon-like peptide-1 receptor agonist effects.Physiology & behavior · 2020Article
- Models of hydration and nutrition require environmental data.Public health nutrition · 2020Article
- Total body water by BIA in children and young adults with normal and excessive weight.PloS one · 2020Article
- Measuring Human Water Needs.American journal of human biology : the official journal of the Human Biology Council · 2020Article
- Unexplained Variance in Hydration Study.Nutrients · 2019Article
- Cross-sectional association of dietary water intakes and sources, and adiposity: National Adult Nutrition Survey, the Republic of Ireland.European journal of nutrition · 2019Article
- Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAdequate water intake is critical to physiologic and cognitive functioning. Although water requirements increase with body size, it remains unclear whether weight status modifies the relation between water intake and hydration status.
objectiveWe examined how the association between water intake and urine osmolality, which is a hydration biomarker, varied by weight status.
designNHANES cross-sectional data (2009-2012) were analyzed in 9601 nonpregnant adults aged ≥20 y who did not have kidney failure. Weight status was categorized with the use of body mass index on the basis of measured height and weight (underweight or normal weight, overweight, and obesity). Urine osmolality was determined with the use of freezing-point depression osmometry. Hypohydration was classified according to the following age-dependent formula: ≥831 mOsm/kg - [3.4 × (age - 20 y)]. Total water intake was determined with the use of a 24-h dietary recall and was dichotomized as adequate or low on the basis of the Institute of Medicine's adequate intake recommendations for men and women (men: ≥3.7 or <3.7 L; nonlactating women: ≥2.7 or <2.7 L; lactating women: ≥3.8 or <3.8 L for adequate or low intakes, respectively). We tested interactions and conducted linear and log-binomial regressions.
resultsTotal water intake (P = 0.002), urine osmolality (P < 0.001), and hypohydration prevalence (P < 0.001) all increased with higher weight status. Interactions between weight status and water intake status were significant in linear (P = 0.005) and log-binomial (P = 0.015) models, which were then stratified. The prevalence ratio of hypohydration between subjects with adequate water intake and those with low water intake was 0.56 (95% CI: 0.43, 0.73) in adults who were underweight or normal weight, 0.67 (95% CI: 0.57, 0.79) in adults who were overweight, and 0.78 (95% CI: 0.70, 0.88) in adults who were obese.
conclusionOn a population level, obesity modifies the association between water intake and hydration status.
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