Evidence map›Paper›PMID 27935477›Full record

ArticleeLife2016

Regulation of B cell fate by chronic activity of the IgE B cell receptor.

Zhiyong Yang, Marcus J Robinson, Xiangjun Chen, Geoffrey A Smith, Jack Taunton, Wanli Liu, Christopher D C Allen

Open access · goldAbstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 103 citations in OpenAlex.

  1. Review
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  4. Article
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  7. Review
  8. Review
  9. Article
  10. Review
  11. Whence and wherefore IgE?Immunological reviews · 2024
    Review
  12. Article
  13. Origins and diversity of pan-isotype human bone marrow plasma cells.bioRxiv : the preprint server for biology · 2024
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. B cell receptor ligation induces IgE plasma cell elimination.The Journal of experimental medicine · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Zhiyong YangCardiovascular Research Institute, University of California, San Francisco, San Francisco, United States.
Marcus J RobinsonCardiovascular Research Institute, University of California, San Francisco, San Francisco, United States.ORCID 0000-0001-5677-3078
Xiangjun ChenMOE Key Laboratory of Protein Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, School of Life Sciences, Institute for Immunology, Tsinghua University, Beijing, China.
Geoffrey A SmithDepartment of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.ORCID 0000-0002-1638-4219
Jack TauntonDepartment of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.
Wanli LiuMOE Key Laboratory of Protein Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, School of Life Sciences, Institute for Immunology, Tsinghua University, Beijing, China.ORCID 0000-0003-0395-2800
Christopher D C AllenCardiovascular Research Institute, University of California, San Francisco, San Francisco, United States.ORCID 0000-0002-1879-9047
University of California, San Francisco · USTsinghua University · CN

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007618 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANDERSON, MARK S · 1985 to 2020
$29.6M
RESEARCH TRAINING IN CHEMISTRY AND CHEMICAL BIOLOGYT32GM064337 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIK, CHARLES SCOTT · 2002 to 2021
$7.8M
Dissecting the role of Janus Kinases in Common Cytokine Receptor y-chain signaling in T-cells using chemical geneticsF30AI120517 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SMITH, GEOFFREY ALEXANDER · 2015 to 2018
$145k
NIAID NIH HHS F30 AI120517NIGMS NIH HHS T32 GM007618NIGMS NIH HHS T32 GM064337
6 · The paper itself

Abstract

IgE can trigger potent allergic responses, yet the mechanisms regulating IgE production are poorly understood. Here we reveal that IgE

Indexed as

Lymphocyte ActivationAnimalsApoptosisB-LymphocytesCell ProliferationCells, CulturedImmunoglobulin EMice, Inbred C57BLReceptors, IgEImmunoglobulin EReceptors, IgEantigen presentationB cell receptorcell biologygerminal centerimmunologymouseplasma cellsignalingT cell help

Identifiers

PMID27935477
PMCPMC5207771
OpenAlexW2560256102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.