Evidence map›Paper›PMID 27935322›Full record

ArticleBehavioral sleep medicine

Physical Activity and Cognition: A Mediating Role of Efficient Sleep.

Kristine A Wilckens, Kirk I Erickson, Mark E Wheeler

Abstract read
In one paragraph

Article in Behavioral sleep medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

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  14. Physical activity and arterial stiffness: is body fat a mediator?European journal of applied physiology · 2024
    Article
  15. The Interactive Role of Sleep and Circadian Rhythms in Episodic Memory in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kristine A Wilckensa Department of Psychiatry , University of Pittsburgh School of Medicine , Pittsburgh , Pennsylvania.
Kirk I Ericksonb Department of Psychology , University of Pittsburgh , Pittsburgh , Pennsylvania.
Mark E Wheelerc School of Psychology , Georgia Institute of Technology , Atlanta , Georgia.

Funding

CLINICAL RESEARCH TRAINING IN LATE-LIFE MOOD DISORDERST32MH019986 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOWARD J AIZENSTEIN, Carmen Andreescu · 1997 to 2026
$6.9M
Predoctoral Training Program in Behavioral Brain ResearchT32GM081760 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FIEZ, JULIE A, HOLT, LORI L · 2007 to 2021
$4.3M
Functional Imaging of Perceptual Decision Making and Evidence AccumulationR01MH086492 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WHEELER, MARK EDWARD · 2010 to 2013
$1.4M
Slow-wave sleep and executive network function in older adultsK01AG049879 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WILCKENS, KRISTINE ANN · 2016 to 2020
$713k
NIA NIH HHS K01 AG049879NIGMS NIH HHS T32 GM081760NIMH NIH HHS R01 MH086492NIMH NIH HHS T32 MH019986
6 · The paper itself

Abstract

objectivePhysical activity benefits executive control, but the mechanism through which this benefit occurs is unclear. Sleep is a candidate mechanism given that it improves with exercise and has restorative effects on the prefrontal cortex. The present cross-sectional study examined the mediating role of sleep in the relationship between physical activity and executive control in young and older adults.

participantsYoung (n = 59) and older (n = 53) community-dwelling adults ages 21-30 and 55-80.

methodsParticipants wore an accelerometer for one week to assess sleep efficiency, total sleep time, and physical activity, operationalized as metabolic equivalent of task (METs) during time spent awake. Cognition was assessed in the laboratory across multiple measures of executive control, memory recall, and processing speed. Mediation analyses tested the role of sleep efficiency in the cross-sectional relationship between METs and cognitive performance accounting for age, sex, and education.

resultsMETs were significantly associated with performance before, but not after accounting for covariates. METs were associated with sleep efficiency but not total sleep time. Sleep efficiency, but not total sleep time, mediated the relationship between METs and working memory, switching, verbal ability and fluency, and recall. Age group did not moderate the mediating role of sleep efficiency in the relationship between METs and performance.

conclusionSleep efficiency is one pathway by which physical activity may be associated with executive control across young and older adults.

Indexed as

AdultAgedAged, 80 and overCognitionCross-Sectional StudiesExecutive FunctionExerciseFemaleHumansMaleMiddle AgedSleepYoung Adult

Identifiers

PMID27935322
PMCPMC5466488

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.