ArticleJournal of biomedical materials research. Part A2017
Tailoring the physicochemical and shape memory properties of the biodegradable polymer poly(glycerol dodecanoate) via curing conditions.
Article in Journal of biomedical materials research. Part A, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Body-responsive shape-memory polymers for biomedical applications.Bioactive materials · 2026Review
- A Tissue-Compliant Shape-Memory Composite Membrane for Cardiac Occluders.Bioengineering (Basel, Switzerland) · 2026Article
- Thermal Post-Processing of 3D-Printed Poly(glycerol dodecanedioate) Controls Mechanics and Shape Memory Properties.Polymer science & technology (Washington, D.C.) · 2025Article
- Ligand Composition and Coating Density Co-Modulate the Chondrocyte Function on Poly(glycerol-dodecanedioate).Journal of functional biomaterials · 2023Article
- Innovative design of minimal invasive biodegradable poly(glycerol-dodecanoate) nucleus pulposus scaffold with function regeneration.Nature communications · 2023Article
- Sterilization effects on poly(glycerol dodecanedioate): A biodegradable shape memory elastomer for biomedical applications.Journal of biomedical materials research. Part B, Applied biomaterials · 2023Article
- Comments on Innovative design of minimal invasive biodegradable poly(glycerol-dodecanoate) nucleus pulposus scaffold with function regeneration.Biomaterials translational · 2023Article
- Relationship between mechanical load and surface erosion degradation of a shape memory elastomer poly(glycerol-dodecanoate) for soft tissue implant.Regenerative biomaterials · 2023Article
- 4D Printing of shape-memory polymeric scaffolds for adaptive biomedical implantation.Acta biomaterialia · 2021Article
- Modulating nonlinear elastic behavior of biodegradable shape memory elastomer and small intestinal submucosa(SIS) composites for soft tissue repair.Journal of the mechanical behavior of biomedical materials · 2020Article
- Degradation properties of a biodegradable shape memory elastomer, poly(glycerol dodecanoate), for soft tissue repair.PloS one · 2020Article
- Innovative interventional catheterization techniques for congenital heart disease.Translational pediatrics · 2018Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
A major challenge in the repair and regeneration of soft tissue damage occurring as a result of aging, injury, or disease is recapitulating the biomechanical properties of the native tissue. Ideally, a candidate biomaterial for soft tissue engineering applications should be biocompatible, nonlinearly elastic to match soft tissue mechanical behavior, biodegradable to enable tissue remodeling, and tailorable to achieve a range of nonlinear elastic mechanical properties to match specific soft tissues. In addition, for cardiac and other applications, the biomaterial should have shape memory characteristics to facilitate minimally invasive and/or catheter-based delivery. Poly(glycerol dodecanoate) (PGD) is a shape memory material that has nonlinear elastic properties at body temperature and elastic-plastic behavior at room temperature. In this study, we investigated the effects of curing conditions on the nonlinear elastic, shape memory, and biocompatibility properties of PGD. Increased curing and crosslinking resulted in an increase in both the initial stiffness and the nonlinear strain stiffening behavior of PGD. After shape fixation at 60% strain, 100% shape recovery was achieved within 1 min at body temperature for all conditions tested. Polymer curing had no adverse effects on the cellular biocompatibility or non-hemolytic characteristics of PGD, indicating the potential suitability of these formulations for blood-contacting device applications. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1618-1623, 2017.
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