ArticleLab on a chip2017
3D printed metal molds for hot embossing plastic microfluidic devices.
Article in Lab on a chip, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 71 citations in OpenAlex.
- Effect of Build Orientation on Surface Finish and Hydrodynamic Stability of Inkjet 3D-Printed Microfluidic Channels.Polymers · 2025Article
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- Rapid prototyping of thermoplastic microfluidic devices via SLA 3D printing.Scientific reports · 2024Article
- Demonstration of a Transparent and Adhesive Sealing Top for Microfluidic Lab-Chip Applications.Sensors (Basel, Switzerland) · 2024Article
- 3D Printing of Individualized Microfluidic Chips with DLP-Based Printer.Materials (Basel, Switzerland) · 2023Article
- Microfluidic Organ-on-A-chip: A Guide to Biomaterial Choice and Fabrication.International journal of molecular sciences · 2023Review
- Merits and advances of microfluidics in the pharmaceutical field: design technologies and future prospects.Drug delivery · 2022Review
- Compatibility of Popular Three-Dimensional Printed Microfluidics Materials with In Vitro Enzymatic Reactions.ACS applied bio materials · 2022Article
- Microfluidic SERS devices: brightening the future of bioanalysis.Discover materials · 2022Review
- Droplet Microfluidics for Tumor Drug-Related Studies and Programmable Artificial Cells.Global challenges (Hoboken, NJ) · 2021Review
- Fabrication Methods for Microfluidic Devices: An Overview.Micromachines · 2021Review
- Advanced Fabrication Techniques of Microengineered Physiological Systems.Micromachines · 2020Review
- Article
- A novel abrasive water jet machining technique for rapid fabrication of three-dimensional microfluidic components.Biomicrofluidics · 2020Article
- 3D-MID Technology for Surface Modification of Polymer-Based Composites: A Comprehensive Review.Polymers · 2020Review
- Optical Etching to Pattern Microstructures on Plastics by Vacuum Ultraviolet Light.Materials (Basel, Switzerland) · 2020Article
- A disposable acoustofluidic chip for nano/microparticle separation using unidirectional acoustic transducers.Lab on a chip · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Plastics are one of the most commonly used materials for fabricating microfluidic devices. While various methods exist for fabricating plastic microdevices, hot embossing offers several unique advantages including high throughput, excellent compatibility with most thermoplastics and low start-up costs. However, hot embossing requires metal or silicon molds that are fabricated using CNC milling or microfabrication techniques which are time consuming, expensive and required skilled technicians. Here, we demonstrate for the first time the fabrication of plastic microchannels using 3D printed metal molds. Through optimization of the powder composition and processing parameters, we were able to generate stainless steel molds with superior material properties (density and surface finish) than previously reported 3D printed metal parts. Molds were used to fabricate poly(methyl methacrylate) (PMMA) replicas which exhibited good feature integrity and replication quality. Microchannels fabricated using these replicas exhibited leak-free operation and comparable flow performance as those fabricated from CNC milled molds. The speed and simplicity of this approach can greatly facilitate the development (i.e. prototyping) and manufacture of plastic microfluidic devices for research and commercial applications.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.