Evidence map›Paper›PMID 27934929›Full record

ArticleScientific reports2016

Use of polyvinylpyrrolidone-iodine solution for sterilisation and preservation improves mechanical properties and osteogenesis of allografts.

Yantao Zhao, Xiantong Hu, Zhonghai Li, Fuli Wang, Yang Xia, Shuxun Hou, Hongbin Zhong, Feimin Zhang, Ning Gu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yantao ZhaoBeijing Engineering Research Center of Orthopaedic Implants, First Affiliated Hospital of CPLA General Hospital, Beijing 100048, P. R. China.
Xiantong HuBeijing Engineering Research Center of Orthopaedic Implants, First Affiliated Hospital of CPLA General Hospital, Beijing 100048, P. R. China.
Zhonghai LiBeijing Engineering Research Center of Orthopaedic Implants, First Affiliated Hospital of CPLA General Hospital, Beijing 100048, P. R. China.
Fuli WangBeijing Engineering Research Center of Orthopaedic Implants, First Affiliated Hospital of CPLA General Hospital, Beijing 100048, P. R. China.
Yang XiaJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing 210029, P. R. China.
Shuxun HouBeijing Engineering Research Center of Orthopaedic Implants, First Affiliated Hospital of CPLA General Hospital, Beijing 100048, P. R. China.
Hongbin ZhongBeijing Engineering Research Center of Orthopaedic Implants, First Affiliated Hospital of CPLA General Hospital, Beijing 100048, P. R. China.
Feimin ZhangJiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing 210029, P. R. China.
Ning GuState Key Laboratory of Bioelectronics, Jiangsu Key Laboratory of Biomaterials and Devices, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, P. R. China.
First Affiliated Hospital of Chinese PLA General Hospital · CNNanjing Medical University · CNSoutheast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allografts eliminate the disadvantages associated with autografts and synthetic scaffolds but are associated with a disease-transmission risk. Therefore, allograft sterilisation is crucial. We aimed to determine whether polyvinylpyrrolidone-iodine (PVP-I) can be used for sterilisation and as a new wet-preservation method. PVP-I-sterilised and preserved allografts demonstrated improved mechanical property, osteogenesis, and excellent microbial inhibition. A thigh muscle pouch model of nude mice showed that PVP-I-preserved allografts demonstrated better ectopic formation than Co

Indexed as

Bone TransplantationPreservation, BiologicalSterilizationAnimalsBiomarkersBone and BonesImmunohistochemistryMaleMechanical PhenomenaMiceOrgan Preservation SolutionsOsteogenesisPovidone-IodineTransplantation, HomologousBiomarkersOrgan Preservation SolutionsPovidone-Iodine

Identifiers

PMID27934929
PMCPMC5146663
OpenAlexW2560600098

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.