ArticleScientific reports2016
High-speed swept source optical coherence Doppler tomography for deep brain microvascular imaging.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Double-helix optical point spread function enables real-time mesoscopic 3D functional microangiography in the living mouse brain and skull.Nature communications · 2026Article
- Ultrafast two-photon fluorescence imaging of cerebral blood circulation in the mouse brain in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Stabilizing the phase of swept-source optical coherence tomography by a wrapped Gaussian mixture model.Optics letters · 2021Article
- Validation of red blood cell flux and velocity estimations based on optical coherence tomography intensity fluctuations.Scientific reports · 2020Article
- Cocaine Decreases Spontaneous Neuronal Activity and Increases Low-Frequency Neuronal and Hemodynamic Cortical Oscillations.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Akinetic swept-source optical coherence tomography based on a pulse-modulated active mode locking fiber laser for human retinal imaging.Scientific reports · 2018Article
- Deep brain optical coherence tomography angiography in mice: in vivo, noninvasive imaging of hippocampal formation.Scientific reports · 2018Article
- Complex regression Doppler optical coherence tomography.Journal of biomedical optics · 2018Article
- Automated segmentation and quantification of OCT angiography for tracking angiogenesis progression.Biomedical optics express · 2017Article
- Robust numerical phase stabilization for long-range swept-source optical coherence tomography.Journal of biophotonics · 2017Article
- Wide-field high-speed space-division multiplexing optical coherence tomography using an integrated photonic device.Biomedical optics express · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Noninvasive microvascular imaging using optical coherence Doppler tomography (ODT) has shown great promise in brain studies; however, high-speed microcirculatory imaging in deep brain remains an open quest. A high-speed 1.3 μm swept-source ODT (SS-ODT) system is reported which was based on a 200 kHz vertical-cavity-surface-emitting laser. Phase errors induced by sweep-trigger desynchronization were effectively reduced by spectral phase encoding and instantaneous correlation among the A-scans. Phantom studies have revealed a significant reduction in phase noise, thus an enhancement of minimally detectable flow down to 268.2 μm/s. Further in vivo validation was performed, in which 3D cerebral-blood-flow (CBF) networks in mouse brain over a large field-of-view (FOV: 8.5 × 5 × 3.2 mm
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Registered trials
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