ArticleScientific reports2016
Effects of dose reduction on bone strength prediction using finite element analysis.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- The Application of Advanced Bone Imaging Technologies in Sports Medicine.Radiology research and practice · 2023Review
- Finite Element Analysis of Osteoporotic and Osteoblastic Vertebrae and Its Association With the Proton Density Fat Fraction From Chemical Shift Encoding-Based Water-Fat MRI - A Preliminary Study.Frontiers in endocrinology · 2022Article
- Drinking Natural Mineral Water Maintains Bone Health in Young Rats With Metabolic Acidosis.Frontiers in nutrition · 2022Article
- MDCT-Based Finite Element Analysis for the Prediction of Functional Spine Unit Strength-An In Vitro Study.Materials (Basel, Switzerland) · 2021Article
- Multi-detector computed tomography (MDCT) imaging: association of bone texture parameters with finite element analysis (FEA)-based failure load of single vertebrae and functional spinal units.Quantitative imaging in medicine and surgery · 2021Article
- MDCT-Based Finite Element Analyses: Are Measurements at the Lumbar Spine Associated with the Biomechanical Strength of Functional Spinal Units of Incidental Osteoporotic Fractures along the Thoracolumbar Spine?Diagnostics (Basel, Switzerland) · 2021Article
- Prediction of Incidental Osteoporotic Fractures at Vertebral-Specific Level Using 3D Non-Linear Finite Element Parameters Derived from Routine Abdominal MDCT.Diagnostics (Basel, Switzerland) · 2021Article
- X-ray-based quantitative osteoporosis imaging at the spine.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Review
- Predicting Vertebral Bone Strength Using Finite Element Analysis for Opportunistic Osteoporosis Screening in Routine Multidetector Computed Tomography Scans-A Feasibility Study.Frontiers in endocrinology · 2020Article
- Finite Element Analysis-Based Vertebral Bone Strength Prediction Using MDCT Data: How Low Can We Go?Frontiers in endocrinology · 2020Article
- MDCT-based Finite Element Analysis of Vertebral Fracture Risk: What Dose is Needed?Clinical neuroradiology · 2019Article
- Neuro-musculoskeletal flexible multibody simulation yields a framework for efficient bone failure risk assessment.Scientific reports · 2019Article
- Bone mineral density assessment using iterative reconstruction compared with quantitative computed tomography as the standard of reference.Scientific reports · 2018Article
- Are CT-Based Finite Element Model Predictions of Femoral Bone Strength Clinically Useful?Current osteoporosis reports · 2018Review
- Effect of radiation dose reduction on texture measures of trabecular bone microstructure: an in vitro study.Journal of bone and mineral metabolism · 2018Article
- Feasibility of opportunistic osteoporosis screening in routine contrast-enhanced multi detector computed tomography (MDCT) using texture analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Article
- Cost-Effectiveness Analysis of CT-Based Finite Element Modeling for Osteoporosis Screening in Secondary Fracture Prevention: An Early Health Technology Assessment in the Netherlands.MDM policy & practiceArticle
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Authors and funding
8 authors.
Funding
Abstract
This study aimed to evaluate the effect of dose reduction, by means of tube exposure reduction, on bone strength prediction from finite-element (FE) analysis. Fresh thoracic mid-vertebrae specimens (n = 11) were imaged, using multi-detector computed tomography (MDCT), at different intensities of X-ray tube exposures (80, 150, 220 and 500 mAs). Bone mineral density (BMD) was estimated from the mid-slice of each specimen from MDCT images. Differences in image quality and geometry of each specimen were measured. FE analysis was performed on all specimens to predict fracture load. Paired t-tests were used to compare the results obtained, using the highest CT dose (500 mAs) as reference. Dose reduction had no significant impact on FE-predicted fracture loads, with significant correlations obtained with reference to 500 mAs, for 80 mAs (R
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