Evidence map›Paper›PMID 27934305›Full record

ArticleInorganic chemistry2016

Gear Up for a pH Shift: A Responsive Iron(II) 2-Amino-6-picolyl-Appended Macrocyclic paraCEST Agent That Protonates at a Pendent Group.

Pavel B Tsitovich, Jordan M Cox, Joseph A Spernyak, Janet R Morrow

Abstract read
In one paragraph

Article in Inorganic chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Isomeric Co(ii) paraCEST agents as pH responsive MRI probes.Dalton transactions (Cambridge, England : 2003) · 2020
    Article
  10. Article
  11. Review
  12. Lanthanide-Based TAngewandte Chemie (International ed. in English) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pavel B TsitovichDepartment of Chemistry, University at Buffalo, the State University of New York , Buffalo, New York 14260, United States.
Jordan M CoxDepartment of Chemistry, University at Buffalo, the State University of New York , Buffalo, New York 14260, United States.
Joseph A SpernyakDepartment of Cell Stress Biology, Roswell Park Cancer Institute , Buffalo, New York 14263, United States.
Janet R MorrowDepartment of Chemistry, University at Buffalo, the State University of New York , Buffalo, New York 14260, United States.

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MARK G FRATTINI · 1985 to 2026
$116.6M
Iron PARACEST MRI Contrast Agents for Monitoring Hyperthermia-based TherapyR03CA175858 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MORROW, JANET RUTH, SPERNYAK, JOSEPH ANDREW · 2014 to 2015
$182k
NCI NIH HHS P30 CA016056NCI NIH HHS R03 CA175858
6 · The paper itself

Abstract

Two high-spin Fe(II) and Co(II) complexes of 1,4,7,10-tetraazacyclododecane (CYCLEN) appended with four 2-amino-6-picolyl groups, denoted as [Fe(TAPC)]

Identifiers

PMID27934305
PMCPMC5553446

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.