Evidence map›Paper›PMID 27934017›Full record

ArticleJournal of the American Chemical Society2016

Helix-Dependent Spin Filtering through the DNA Duplex.

Theodore J Zwang, Sylvia Hürlimann, Michael G Hill, Jacqueline K Barton

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Single-Molecule Electrical Conductance in Z-form DNA:RNA.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  7. Chiral Induced Spin Selectivity.Chemical reviews · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Spin Filtering Along Chiral Polymers.Angewandte Chemie (International ed. in English) · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Theodore J ZwangDivision of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.
Sylvia HürlimannDivision of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.
Michael G HillDivision of Chemistry, Occidental College , Los Angeles, California 90041, United States.
Jacqueline K BartonDivision of Chemistry and Chemical Engineering, California Institute of Technology , Pasadena, California 91125, United States.

Funding

ELECTROCHEMICAL DNA-BASED SENSORSR01GM061077 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI BARTON, JACQUELINE K · 2000 to 2017
$5.2M
NIGMS NIH HHS R01 GM061077
6 · The paper itself

Abstract

Recent work suggests that electrons can travel through DNA and other chiral molecules in a spin-selective manner, but little is known about the origin of this spin selectivity. Here we describe experiments on magnetized DNA-modified electrodes to explore spin-selective electron transport through hydrated duplex DNA. Our results show that the two spins migrate through duplex DNA with a different yield and that spin selectivity requires charge transport through the DNA duplex. Significantly, shifting the same duplex DNA between right-handed B- and left-handed Z-forms leads to a diode-like switch in spin selectivity; which spin moves more efficiently through the duplex depends upon the DNA helicity. With DNA, the supramolecular organization of chiral moieties, rather than the chirality of the individual monomers, determines the selectivity in spin, and thus a conformational change can switch the spin selectivity.

Indexed as

DNAElectrochemical TechniquesElectrodesElectron TransportMethylene BlueOxazinesOxidation-ReductionSilverSilver CompoundsDNAMethylene BlueNile BlueOxazinesSilversilver chlorideSilver Compounds

Identifiers

PMID27934017
PMCPMC5175457

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.