ArticleJournal of the American Chemical Society2016
A Mechanistic Model for Colibactin-Induced Genotoxicity.
Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 76 citations in OpenAlex.
- Chloroethylnitrosourea analogue HJ03 overcomes temozolomide resistance of glioblastoma in mice through induction of ferroptosis and apoptosis.Acta pharmacologica Sinica · 2026Article
- Synthesis and Biological Evaluation of Colibactin Derivatives.ACS chemical biology · 2026Article
- Mutagenic Potentials of DNA Interstrand Cross-Links Induced by 7,8-Dihydro-8-Oxoadenine.Molecules (Basel, Switzerland) · 2026Article
- Colibactin (Frontiers in microbiology · 2026Article
- Mitochondria-Targeted Temozolomide Probe for Overcoming MGMT-Mediated Resistance in Glioblastoma.Chembiochem : a European journal of chemical biology · 2025Article
- Review
- Current understandings of colibactin regulation.Microbiology (Reading, England) · 2024Review
- Review
- Structure Elucidation of Secondary Metabolites: Current Frontiers and Lingering Pitfalls.Accounts of chemical research · 2023Article
- Maternal and Child Health, Non-Communicable Diseases and Metabolites.Metabolites · 2023Review
- Structure and function of prodrug-activating peptidases.Biochimie · 2023Review
- Delivery, structure, and function of bacterial genotoxins.Virulence · 2022Review
- Novel Imidazotetrazine Evades Known Resistance Mechanisms and Is Effective against Temozolomide-Resistant Brain Cancer in Cell Culture.ACS chemical biology · 2022Article
- The microbiome-product colibactin hits unique cellular targets mediating host-microbe interaction.Frontiers in pharmacology · 2022Review
- Mother-to-infant transmission of the carcinogenic colibactin-producing bacteria.BMC microbiology · 2021Article
- Bacterial Toxins Are a Never-Ending Source of Surprises: From Natural Born Killers to Negotiators.Toxins · 2021Review
- Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.Nature communications · 2021Article
- Employing chemical synthesis to study the structure and function of colibactin, a "dark matter" metabolite.Natural product reports · 2020Review
- Structure and bioactivity of colibactin.Bioorganic & medicinal chemistry letters · 2020Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Precolibactins and colibactins represent a family of natural products that are encoded by the clb gene cluster and are produced by certain commensal, extraintestinal, and probiotic E. coli. clb
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.