ArticleInternational journal of implant dentistry2016
Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study.
Article in International journal of implant dentistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Antimicrobial photodynamic therapy as adjunct to non-surgical periodontal treatment in smokers: a randomized clinical trial.Clinical oral investigations · 2019Trial
- A Study of the Effects of Oleuropein and Polydatin Association on Muscle and Bone Metabolism.Biomolecules · 2025Article
- Masticatory Efficiency of Thermoplastic Versus Conventional Acrylic Resin Mandibular Implant Overdenture With Bar/Clip Attachment.International journal of dentistry · 2025Article
- Diagnostic and Prognostic Value of Indicators of Bone Metabolism Markers in Patients Following Mandibulectomy and Free Fibula Flap Reconstruction with Endosteal Implants.Journal of maxillofacial and oral surgery · 2024Article
- Integrating enzyme-nanoparticles bring new prospects for the diagnosis and treatment of immune dysregulation in periodontitis.Frontiers in cellular and infection microbiology · 2024Review
- Selected osteointegration markers in different timeframes after dental implantation: findings and prognostic value.Acta biochimica Polonica · 2024Article
- Association of sex steroid hormones and new bone formation rate after iliac onlay grafting: a prospective clinical pilot study.International journal of implant dentistry · 2022Article
- Clinical Validation of Dental Implant Stability by Newly Designed Damping Capacity Assessment Device during the Healing Period.Medicina (Kaunas, Lithuania) · 2022Article
- Effects of smoking on the bone alkaline phosphatase in peri-implant crevicular fluid and implant stability quotient around implants before loading.Odontology · 2022Article
- A collagen membrane influences bone turnover marker in vivo after bone augmentation with xenogenic bone.Head & face medicine · 2020Article
- Influence of Resonance Frequency Analysis (RFA) Measurements for Successful Osseointegration of Dental Implants During the Healing Period and Its Impact on Implant Assessed by Osstell Mentor Device.Open access Macedonian journal of medical sciences · 2019Article
- Comparative study of stress characteristics in surrounding bone during insertion of dental implants of three different thread designs: A three-dimensional dynamic finite element study.Clinical and experimental dental research · 2019Article
- The rate and stability of mandibular block bone graft in recent 5 years.Maxillofacial plastic and reconstructive surgery · 2017Article
- RUNX2 and ALP expression in osteoblast cells exposed by PMMA-HAp combination: An in vitro study.Journal of oral biology and craniofacial researchArticle
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Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe purposes of this study were to examine the correlation between the stability of dental implants and bone formation markers during the healing period and to monitor the stability of dental implants using the resonance frequency analysis (RFA) method. The null hypothesis of the study is no correlation between the stability of dental implant and bone formation markers.
methodsThe study is a prospective clinical study during the 3-month healing period of implant. At implant placement (PW Plus, Nakhon Pathom, Thailand) and after 1, 2, 3, 4, 6, 8, 10, and 12 weeks, RFA assessments were performed and gingival (GCF)/peri-implant crevicular fluids (PICF) were collected from ten patients. The level of osteocalcin (OC) was measured by using ELISA kits, and the level of alkaline phosphatase (ALP) activity was measured by colorimetric analysis. Repeated measures analysis of variance, the Friedman test, the Mann-Whitney U test, and the Pearson correlation were performed for data analysis.
resultsThere was a statistical decrease in the mean implant stability quotient (ISQ) values between 1 and 3 weeks (P < 0.05). The ISQ values recovered to the initial values at 4 weeks. There was no statistical difference in the ALP level at each measurement, while there was a statistical increase in the OC level at 6, 8, 10, and 12 weeks when compared with 1 week (P < 0.05). There was a significant correlation between ALP levels and ISQ values (r = 0.226, P < 0.05). There was a statistically significant correlation between OC levels and ISQ values at 1-12 weeks (r = 0.245, P < 0.05).
conclusionsThe ISQ values were weakly correlated with both ALP and OC. The three-thread-design implant showed a high stability through healing period.
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