Evidence map›Paper›PMID 27933550›Full record

ArticleNeurochemical research2017

Effect of Variable Doses of Zinc Oxide Nanoparticles on Male Albino Mice Behavior.

Javeria Zahra, Shahid Iqbal, Kiran Zahra, Zulha Javed, Muhammad Aslam Shad, Atif Akbar, Muhammad Naeem Ashiq, Furhan Iqbal

Abstract read
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In one paragraph

Article in Neurochemical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Magnesium and Zinc Oxide Nanoparticles fromMolecules (Basel, Switzerland) · 2022
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Javeria ZahraInstitute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan.
Shahid IqbalInstitute of Pure and Applied Biology, Zoology Division, Bahauddin Zakariya University, Multan, Pakistan.
Kiran ZahraInstitute of Pure and Applied Biology, Zoology Division, Bahauddin Zakariya University, Multan, Pakistan.
Zulha JavedInstitute of Pure and Applied Biology, Zoology Division, Bahauddin Zakariya University, Multan, Pakistan.
Muhammad Aslam ShadDepartment of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.
Atif AkbarDepartment of Statistics, Bahauddin Zakariya University, Multan, Pakistan.
Muhammad Naeem AshiqInstitute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan. naeembzu@bzu.edu.pk.
Furhan IqbalInstitute of Pure and Applied Biology, Zoology Division, Bahauddin Zakariya University, Multan, Pakistan. furhan.iqbal@bzu.edu.pk.
Bahauddin Zakariya University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc oxide nanoparticles (ZnO NPs) have diverse utility these days ranging from being part of nanosensors to be ingredient of cosmetics. Present study was designed to report the effect of variable doses of ZnO NPs on selected aspects of male albino mice behavior. Nano particles were synthesized by sol-gel auto-combustion method (Data not shown here). 10 week old male albino mice were divided into four experimental groups; group A, B and C were orally supplemented with 50 (low dose), 300 (medium dose) and 600 mg/ml solvent/kg body weight (high dose) of ZnO NPs for 4 days. Group D (control) orally received 0.2 M sodium phosphate buffer (solvent for ZnO NPs) for the same duration. A series of neurological tests (Rota rod, open field, novel object and light-dark box test) were conducted in all groups and performance was compared between ZnO NPs treated and control group. Muscular functioning during rota rod test was significantly improved in all ZnO NPs treated mice as compared to control group. While no significant differences in open field, novel object and light-dark box test performance were observed when data from studied parameters of specific ZnO NPs treatment were compared with the control group indicating that applied doses of ZnO NPs did not affect the exploratory, anxiolytic behavior and object recognition capability of adult male albino mice.

Indexed as

AnimalsDose-Response Relationship, DrugExploratory BehaviorMaleMiceNanoparticlesRecognition, PsychologyTreatment OutcomeZinc OxideZinc OxideAlbino miceLight–dark box testNovel object recognition testOpen field testRota rod testZinc oxide

Identifiers

PMID27933550
OpenAlexW2560413351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.