Evidence map›Paper›PMID 27933314›Full record

ArticleMolecular therapy oncolytics2016

Tunneling nanotubes: an alternate route for propagation of the bystander effect following oncolytic viral infection.

Justin Ady, Venugopal Thayanithy, Kelly Mojica, Phillip Wong, Joshua Carson, Prassanna Rao, Yuman Fong, Emil Lou

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy oncolytics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Tunneling Nanotubes: Implications for Chemoresistance.Results and problems in cell differentiation · 2024
    Review
  5. Mechanisms of Intracellular Communication in Cancer and Pathogen Spreading.Results and problems in cell differentiation · 2024
    Review
  6. Article
  7. Review
  8. Microbiology spectrum · 2022
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. HSV-TK Expressing Mesenchymal Stem Cells Exert Inhibitory Effect on Cervical Cancer Model.International journal of molecular and cellular medicine · 2020
    Article
  17. Frontiers in oncology · 2020
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Justin AdyDepartment of Surgery, Memorial Sloan-Kettering Cancer Center , New York, New York, USA.
Venugopal ThayanithyDepartment of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota , Minneapolis, Minnesota, USA.
Kelly MojicaDepartment of Surgery, Memorial Sloan-Kettering Cancer Center , New York, New York, USA.
Phillip WongDepartment of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota , Minneapolis, Minnesota, USA.
Joshua CarsonDepartment of Surgery, Memorial Sloan-Kettering Cancer Center , New York, New York, USA.
Prassanna RaoDepartment of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota , Minneapolis, Minnesota, USA.
Yuman FongDepartment of Surgery, Memorial Sloan-Kettering Cancer Center , New York, New York, USA.
Emil LouDepartment of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota , Minneapolis, Minnesota, USA.
Memorial Sloan Kettering Cancer Center · USUniversity of Minnesota · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
SURGICAL ONCOLOGY RESEARCH TRAINING PROGRAMT32CA009501 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Babak J Mehrara · 1985 to 2026
$7.7M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)KL2TR000113 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$5.4M
NCATS NIH HHS KL2 TR000113NCATS NIH HHS UL1 TR000114NCI NIH HHS P30 CA008748NCI NIH HHS T32 CA009501
6 · The paper itself

Abstract

Tunneling nanotubes (TNTs) are ultrafine, filamentous actin-based cytoplasmic extensions which form spontaneously to connect cells at short and long-range distances. We have previously described long-range intercellular communication via TNTs connecting mesothelioma cells

Identifiers

PMID27933314
PMCPMC5142513
OpenAlexW2560126927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.