Evidence map›Paper›PMID 27933064›Full record

ArticleFrontiers in immunology2016

Systemic Expression of Notch Ligand Delta-Like 4 during Mycobacterial Infection Alters the T Cell Immune Response.

Matthew A Schaller, Ronald M Allen, Soichiro Kimura, Cheryl L Day, Steven L Kunkel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Notch Signaling in Acute Inflammation and Sepsis.International journal of molecular sciences · 2023
    Review
  4. Notch signaling pathway involved inFrontiers in cellular and infection microbiology · 2023
    Article
  5. Article
  6. iScience · 2022
    Article
  7. Elevated Notch ligands in serum are associated with HIV/TB coinfection.Journal of clinical tuberculosis and other mycobacterial diseases · 2021
    Article
  8. Notch signaling pathway in infectious diseases: role in the regulation of immune response.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Matthew A SchallerDepartment of Pathology, University of Michigan Medical School , Ann Arbor, MI , USA.
Ronald M AllenDepartment of Pathology, University of Michigan Medical School , Ann Arbor, MI , USA.
Soichiro KimuraDepartment of Microbiology and Infectious Diseases, Toho University School of Medicine , Tokyo , Japan.
Cheryl L DayDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA; South African Tuberculosis Vaccine Initiative (SATVI), Institute of Infectious Diseases and Molecular Medicine, School of Child and Adolescent Health, University of Cape Town, Observatory, South Africa.
Steven L KunkelDepartment of Pathology, University of Michigan Medical School , Ann Arbor, MI , USA.
University of Michigan–Ann Arbor · USEmory University · USToho University · JP

Funding

Cytokine-induced epigenetic changes during chronic lung diseaseR01HL112897 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DOU, YALI, KUNKEL, STEVEN LYNN · 2013 to 2016
$2.2M
Mechanisms of Immune Regulation in Mycobacterium Tuberculosis InfectionR01AI083156 · NIAID · UNIVERSITY OF CAPE TOWN · PI DAY, CHERYL LIANE · 2009 to 2012
$415k
NHLBI NIH HHS R01 HL112897NIAID NIH HHS R01 AI083156
6 · The paper itself

Abstract

The Notch ligand delta-like 4 (DLL4) is known to fine-tune the CD4

Indexed as

hematopoiesismonocytesNotchtuberculosis

Identifiers

PMID27933064
PMCPMC5121470
OpenAlexW2551698937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.