ArticleFrontiers in microbiology2016
Clay Components in Soil Dictate Environmental Stability and Bioavailability of Cervid Prions in Mice.
Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Digging into Soil: Effects of Soil Texture on RT-QuIC Performance for Environmental Prion Surveillance.Environmental science & technology · 2026Article
- White-tailed deer scavenging community in a chronic wasting disease-endemic region and considerations for prion movement.Scientific reports · 2026Article
- Detection of chronic wasting disease prions in soil at an illegal white-tailed deer carcass disposal site.Prion · 2025Article
- RT-QuIC optimization for prion detection in soils.MethodsX · 2025Article
- Prion Partitioning and Persistence in Environmental Waters.Environmental science & technology · 2025Article
- Tracking Prions by RT-QuIC: An Update.Sub-cellular biochemistry · 2025Review
- Review
- No evidence of uptake or propagation of reindeer CWD prions in environmentally exposed sheep.Acta veterinaria Scandinavica · 2022Article
- Modeling the Impact of Climate Change on Cervid Chronic Wasting Disease in Semi-Arid South Texas.Frontiers in epidemiology · 2022Article
- Article
- Long-Term Incubation PrPPathogens (Basel, Switzerland) · 2020Article
- Differential gene expression in chronic wasting disease-positive white-tailed deer (Ecology and evolution · 2019Article
- Article
- How do PrPPathogens (Basel, Switzerland) · 2017Review
- The Ecology of Prions.Microbiology and molecular biology reviews : MMBR · 2017Review
- The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
Chronic wasting disease (CWD) affects cervids and is the only known prion disease to affect free-ranging wildlife populations. CWD spread continues unabated, and exact mechanisms of its seemingly facile spread among deer and elk across landscapes in North America remain elusive. Here we confirm that naturally contaminated soil contains infectious CWD prions that can be transmitted to susceptible model organisms. We show that smectite clay content of soil potentiates prion binding capacity of different soil types from CWD endemic and non-endemic areas, likely contributing to environmental stability of bound prions. The smectite clay montmorillonite (Mte) increased prion retention and bioavailability
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.