Evidence map›Paper›PMID 27933019›Full record

ArticleFrontiers in psychology2016

Reduced Working Memory Mediates the Link between Early Institutional Rearing and Symptoms of ADHD at 12 Years.

Florin Tibu, Margaret A Sheridan, Katie A McLaughlin, Charles A Nelson, Nathan A Fox, Charles H Zeanah

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Florin TibuInstitute of Child Development Bucharest, Romania.
Margaret A SheridanDepartment of Psychology and Neuroscience, University of North Carolina, Chapel Hill NC, USA.
Katie A McLaughlinDepartment of Psychology, University of Washington, Seattle WA, USA.
Charles A NelsonHarvard Medical School - Boston Children's Hospital - Harvard Center on the Developing Child - Harvard Graduate School of Education, Boston MA, USA.
Nathan A FoxDepartment of Human Development and Quantitative Methodology, University of Maryland, College Park MD, USA.
Charles H ZeanahDepartment of Psychiatry and Behavioral Sciences, Tulane University School of Medicine, New Orleans LA, USA.
Harvard University · USTulane University · USUniversity of Maryland, College Park · USUniversity of North Carolina at Chapel Hill · USUniversity of Washington · US

Funding

The Relation Between Early Psychosocial Deprivation and Mental Health at 12 YearsR01MH091363 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI FOX, NATHAN A, NELSON, CHARLES ALEXANDER · 2010 to 2024
$9.2M
Mouse Neurodevelopmental Behavior CoreU54HD090255 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI POMEROY, SCOTT LOREN · 2016 to 2020
$5.2M
NICHD NIH HHS U54 HD090255NIMH NIH HHS R01 MH091363
6 · The paper itself

Abstract

Children who are raised in institutions show severe delays across multiple domains of development and high levels of psychopathology, including attention deficit/hyperactivity disorder (ADHD). Low performance in executive functions (EFs) are also common in institutionally reared children and often do not remediate following improvements in the caregiving environment. ADHD symptomatology also remains elevated even after children are removed from institutional care and placed in families. We investigate whether poor EF is a mechanism explaining elevated rates of ADHD in children reared in institutional settings in the Bucharest Early Intervention Project (BEIP). In the current study, we examine the potentially mediating role of poor EF in the association between institutionalization and symptoms of ADHD at age 12 years. A total of 107 children were assessed with the Cambridge Neuropsychological Test Automated Battery (CANTAB) on working memory, set-shifting and planning. We also obtained concurrent teacher reports on their levels of ADHD symptoms (inattention and impulsivity separately). Institutionalization strongly predicted elevations in symptoms of inattention and impulsivity at age 12 years (

Indexed as

ADHDchildrenexecutive functioninginstitutionalizationworking memory

Identifiers

PMID27933019
PMCPMC5121247
OpenAlexW2553368082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.