Evidence map›Paper›PMID 27932991›Full record

ArticleFrontiers in physiology2016

Cannabidiol Modulates the Immunophenotype and Inhibits the Activation of the Inflammasome in Human Gingival Mesenchymal Stem Cells.

Rosaliana Libro, Domenico Scionti, Francesca Diomede, Marco Marchisio, Gianpaolo Grassi, Federica Pollastro, Adriano Piattelli, Placido Bramanti, Emanuela Mazzon, Oriana Trubiani

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
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  11. The Use of Compounds Derived fromInternational journal of molecular sciences · 2024
    Review
  12. Article
  13. The NLRP3 inflammasome: a vital player in inflammation and mediating the anti-inflammatory effect of CBD.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Review
  14. Review
  15. Cannabinoids in Periodontology: Where Are We Now?Antibiotics (Basel, Switzerland) · 2023
    Review
  16. Review
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  18. The impact of cannabinoids on inflammasome signaling in HIV-1 infection.NeuroImmune pharmacology and therapeutics · 2023
    Review
  19. Inflammasomes as mediators of inflammation in HIV-1 infection.Translational research : the journal of laboratory and clinical medicine · 2023
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Rosaliana LibroExperimental Neurology Laboratory, IRCCS Centro Neurolesi "Bonino-Pulejo" Messina, Italy.
Domenico SciontiExperimental Neurology Laboratory, IRCCS Centro Neurolesi "Bonino-Pulejo" Messina, Italy.
Francesca DiomedeStem Cells and Regenerative Medicine Laboratory, Department of Medical, Oral and Biotechnological Sciences, University "G. d'Annunzio" Chieti-Pescara, Chieti, Italy.
Marco MarchisioDepartment of Medicine and Aging Sciences, University "G. d'Annunzio" Chieti-Pescara, Chieti, Italy.
Gianpaolo GrassiCouncil for Research and Experimentation in Agriculture - Research Centre for Industrial Crops (CRA-CIN) Rovigo, Italy.
Federica PollastroDipartimento di Scienze del Farmaco, Università del Piemonte Orientale Novara, Italy.
Adriano PiattelliStem Cells and Regenerative Medicine Laboratory, Department of Medical, Oral and Biotechnological Sciences, University "G. d'Annunzio" Chieti-Pescara, Chieti, Italy.
Placido BramantiExperimental Neurology Laboratory, IRCCS Centro Neurolesi "Bonino-Pulejo" Messina, Italy.
Emanuela MazzonExperimental Neurology Laboratory, IRCCS Centro Neurolesi "Bonino-Pulejo" Messina, Italy.
Oriana TrubianiStem Cells and Regenerative Medicine Laboratory, Department of Medical, Oral and Biotechnological Sciences, University "G. d'Annunzio" Chieti-Pescara, Chieti, Italy.
Centro Neurolesi Bonino Pulejo · ITUniversity of Chieti-Pescara · ITResearch Centre for Cereal and Industrial Crops · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Gingival Mesenchymal Stem Cells (hGMSCs) are multipotential cells that can expand and differentiate in culture under specific and standardized conditions. In the present study, we have investigated whether

Indexed as

cannabidiolhuman gingival mesenchymal stem cellsimmunophenotypeinflammasomenext generation sequencing

Identifiers

PMID27932991
PMCPMC5121123
OpenAlexW2556162687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.