Evidence map›Paper›PMID 27932979›Full record

ArticleFrontiers in pharmacology2016

Madagascine Induces Vasodilatation via Activation of AMPK.

Dapeng Chen, Bochao Lv, Sei Kobayashi, Yongjian Xiong, Pengyuan Sun, Yuan Lin, Salvatore Genovese, Francesco Epifano, Shanshan Hou, Fusheng Tang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Dapeng ChenDalian Medical University, Dalian China.
Bochao LvYamaguchi University School of Medicine, Yamaguchi Japan.
Sei KobayashiYamaguchi University School of Medicine, Yamaguchi Japan.
Yongjian XiongCentral Laboratory, the First Affiliated Hospital, Dalian Medical University Dalian, China.
Pengyuan SunDalian Medical University, Dalian China.
Yuan LinDalian Medical University, Dalian China.
Salvatore GenoveseDipartimento di Farmacia, Università degli Studi "G. D'Annunzio" Chieti-Pescara, Chieti Italy.
Francesco EpifanoDipartimento di Farmacia, Università degli Studi "G. D'Annunzio" Chieti-Pescara, Chieti Italy.
Shanshan HouDalian Medical University, Dalian China.
Fusheng TangDalian Medical University, Dalian China.
Yunyan JiDalian Medical University, Dalian China.
Dandan YuDalian Medical University, Dalian China.
Dalian Medical University · CNUniversity of Chieti-Pescara · ITYamaguchi University · JPFirst Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Madagascine (3-isopentenyloxyemodin) can be chemically synthesized or purified from several

Indexed as

AMPKeNOSmadagascinevasoconstrictionvasospasm

Identifiers

PMID27932979
PMCPMC5122745
OpenAlexW2553162995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.