SynthesisInternational journal of chronic obstructive pulmonary disease2016
Effectiveness of neuromuscular electrical stimulation for the rehabilitation of moderate-to-severe COPD: a meta-analysis.
Synthesis in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04792307 (Feasibility RCT of Neuromuscular Electrical Stimulation; an Intervention to Maintain and Improve neuroMuscular Function During Periods of Immobility), which is not on this map. Cited by 16 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Feasibility RCT of Neuromuscular Electrical Stimulation; an Intervention to Maintain and Improve neuroMuscular Function During Periods of Immobility
Who cites it
16 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- 20 years of neuromuscular electrical stimulation in COPD.European respiratory review : an official journal of the European Respiratory Society · 2024Pooled it
- Effectiveness of neuromuscular electrostimulation in COPD subjects on mechanical ventilation. A systematic review and meta-analysis.Clinics (Sao Paulo, Brazil) · 2022Pooled it
- Effects of neuromuscular electrical stimulation on exercise capacity and quality of life in COPD patients: a systematic review and meta-analysis.Bioscience reports · 2020Pooled it
- Effects of whole-body ELECTROMYOSTIMULATION on health and performance: a systematic review.BMC complementary and alternative medicine · 2019Pooled it
- Neuromuscular electrostimulation for adults with chronic obstructive pulmonary disease.The Cochrane database of systematic reviews · 2018Pooled it
- Effects of Neuromuscular Electrical Stimulation Combined with Repetitive Transcranial Magnetic Stimulation on Upper Limb Motor Function Rehabilitation in Stroke Patients with Hemiplegia.Computational and mathematical methods in medicine · 2022Trial
- The history of pulmonary rehabilitation: learning from the past to shape a brighter future.Breathe (Sheffield, England) · 2025Review
- In the era of long COVID, can we seek new techniques for better rehabilitation?Chronic diseases and translational medicine · 2022Article
- Effect of neuromuscular electrical stimulation on the recovery of people with COVID-19 admitted to the intensive care unit: A narrative review.Journal of rehabilitation medicine · 2021Review
- Neuro-Muscular Dentistry: the "diamond" concept of electro-stimulation potential for stomato-gnathic and oro-dental conditions.Head & face medicine · 2021Review
- Effects of neuromuscular electrical stimulation on pulmonary alveola and cytokines in chronic obstructive pulmonary disease (COPD) and skeletal muscle atrophy model mice.Journal of physical therapy science · 2021Article
- Treatment of severe stable COPD: the multidimensional approach of treatable traits.ERJ open research · 2020Review
- Is it possible to reverse frailty in patients with chronic obstructive pulmonary disease?Clinics (Sao Paulo, Brazil) · 2020Review
- Neuromuscular electrical stimulation improves exercise capacity in adult patients with chronic lung disease: a meta-analysis of English studies.Journal of thoracic disease · 2018Article
- Pulmonary Rehabilitation and Exercise Training in Chronic Obstructive Pulmonary Disease.Deutsches Arzteblatt international · 2018Review
- Exercise assessments and trainings of pulmonary rehabilitation in COPD: a literature review.International journal of chronic obstructive pulmonary disease · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePatients with COPD often experience skeletal muscle dysfunction. For those who are unable or unwilling to undertake physical training, neuromuscular electrical stimulation (NMES) may provide an alternative method of rehabilitation. The purpose of this meta-analysis was to investigate the controversial topic of whether this therapy is effective in patients with moderate-to-severe COPD. PATIENTS AND
methodsWe pooled data from nine trials published between January 9, 2002 and January 4, 2016 across PubMed, Embase, Cochrane Central Register of Controlled Trials, Google Scholar, and relevant websites for randomized controlled trials. In these trials, patients with moderate-to-severe COPD were randomly allocated to receive NMES. Primary outcomes were quadricep strength and exercise capacity. The secondary outcome was health-related quality of life.
resultsWe extracted data from 276 patients. NMES contributed to statistically improved quadricep strength (standardized mean difference 1.12, 95% confidence interval [CI] 0.64-1.59,
conclusionNMES appears an effectual means of enhancing quadricep strength and exercise capacity in moderate-to-severe COPD patients. Further research is demanded to clarify its effect on other outcomes and determine the optimal parameters for an NMES program.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.