Evidence map›Paper›PMID 27932587›Full record

ArticleRNA (New York, N.Y.)2017

A divalent cation-dependent variant of the

Matthew W L Lau, Robert J Trachman, Adrian R Ferré-D'Amaré

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  4. An uncommon [KRNA (New York, N.Y.) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Matthew W L LauNational Heart, Lung and Blood Institute, Bethesda, Maryland 20892-8012, USA.
Robert J TrachmanNational Heart, Lung and Blood Institute, Bethesda, Maryland 20892-8012, USA.
Adrian R Ferré-D'AmaréNational Heart, Lung and Blood Institute, Bethesda, Maryland 20892-8012, USA.
National Heart Lung and Blood Institute · US

Funding

RNA: Structure, Biophysics and PhysiologyZIAHL006102 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI FERRÉ-D'AMARÉ, ADRIAN · 2011 to 2025
$14.6M
6 · The paper itself

Abstract

Ribozymes use divalent cations for structural stabilization, as catalytic cofactors, or both. Because of the prominent role of Ca

Indexed as

Base PairingBase SequenceBinding SitesBiocatalysisCalciumCalcium Chelating AgentsCations, DivalentCoenzymesEdetic AcidGlucosamineGlucose-6-PhosphateKineticsMagnesiumNucleic Acid ConformationPhosphorothioate OligonucleotidesProtein BindingCalciumCalcium Chelating AgentsCations, DivalentCoenzymesEdetic AcidGlucosamineglucosamine 6-phosphateGlucose-6-PhosphateMagnesiumPhosphorothioate OligonucleotidesRNARNA, Catalyticcatalytic RNAin vitro selectionmolecular exaptationphosphorothioate interferenceSAXS

Identifiers

PMID27932587
PMCPMC5311495
OpenAlexW2560657065

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.