ReviewMolecular human reproduction2017
Microfluidic analysis of oocyte and embryo biomechanical properties to improve outcomes in assisted reproductive technologies.
Review in Molecular human reproduction, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biomechanics and mechanical signaling in the ovary: a systematic review.Journal of assisted reproduction and genetics · 2018Pooled it
- From Cytoskeletal Remodeling to Oocyte Quality: The Emerging Role of Mechanics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Recent advances in sex-specific reproductive microphysiological systems for the systematic evaluation of assisted reproductive technology.Materials today. Bio · 2026Review
- Non-invasive biomechanical characterization of embryos using microfluidic cantilevers.European biophysics journal : EBJ · 2026Article
- The human Zona-Pellucida shear modulus before and after fertilization and its implications in IVF embryo selection.Scientific reports · 2026Article
- Morphometric Blastocyst Assessment: A Retrospective Study Examining the Relationship Between Blastocyst Diameter and Area and Pregnancy Outcomes in Assisted Reproduction Technology Cycles.Journal of clinical medicine · 2025Article
- Noninvasive characterization of oocyte deformability in microconstrictions.Science advances · 2025Article
- Phenogenetics of cortical granule dynamics during zebrafish oocyte-to-embryo transition.Frontiers in cell and developmental biology · 2025Review
- Hyperelastic models for the human zona pellucida and their implications on shear modulus estimation in the clinical practice.Scientific reports · 2024Article
- Microfluidics-A novel technique for high-quality sperm selection for greater ART outcomes.FASEB bioAdvances · 2024Review
- Multi-cellular engineered living systems to assess reproductive toxicology.Reproductive toxicology (Elmsford, N.Y.) · 2024Review
- Micro/Nanorobotics in In Vitro Fertilization: A Paradigm Shift in Assisted Reproductive Technologies.Micromachines · 2024Review
- Microfluidic chip as a promising evaluation method in assisted reproduction: A systematic review.Bioengineering & translational medicine · 2024Review
- Development and evaluation of a usable blastocyst predictive model using the biomechanical properties of human oocytes.PloS one · 2024Article
- Article
- Revolutionizing the female reproductive system research using microfluidic chip platform.Journal of nanobiotechnology · 2023Review
- Culture conditions in the IVF laboratory: state of the ART and possible new directions.Journal of assisted reproduction and genetics · 2023Review
- Imaging the subcellular viscoelastic properties of mouse oocytes.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Microfluidic techniques for mechanical measurements of biological samples.Biophysics reviews · 2023Review
- Opportunities involving microfluidics and 3D culture systems to theAnimal reproduction · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Measurement of oocyte and embryo biomechanical properties has recently emerged as an exciting new approach to obtain a quantitative, objective estimate of developmental potential. However, many traditional methods for probing cell mechanical properties are time consuming, labor intensive and require expensive equipment. Microfluidic technology is currently making its way into many aspects of assisted reproductive technologies (ART), and is particularly well suited to measure embryo biomechanics due to the potential for robust, automated single-cell analysis at a low cost. This review will highlight microfluidic approaches to measure oocyte and embryo mechanics along with their ability to predict developmental potential and find practical application in the clinic. Although these new devices must be extensively validated before they can be integrated into the existing clinical workflow, they could eventually be used to constantly monitor oocyte and embryo developmental progress and enable more optimal decision making in ART.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.