Evidence map›Paper›PMID 27932501›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2017

Molecular mechanism(s) involved in differential expression of vitamin C transporters along the intestinal tract.

Veedamali S Subramanian, Padmanabhan Srinivasan, Alexis J Wildman, Jonathan S Marchant, Hamid M Said

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Role of vitamin C and SVCT2 in neurogenesis.Frontiers in neuroscience · 2023
    Review
  4. Mediators of inflammation · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Vitamin C and Cardiovascular Disease: An Update.Antioxidants (Basel, Switzerland) · 2020
    Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Veedamali S SubramanianDepartments of Medicine, Physiology, and Biophysics, University of California, Irvine, California; vsubrama@uci.edu.
Padmanabhan SrinivasanDepartments of Medicine, Physiology, and Biophysics, University of California, Irvine, California.
Alexis J WildmanDepartment of Veterans Affairs Medical Center, Long Beach, California; and.
Jonathan S MarchantDepartment of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota.
Hamid M SaidDepartments of Medicine, Physiology, and Biophysics, University of California, Irvine, California.
Long Beach Medical Center · USUniversity of California, Irvine · USUniversity of Minnesota Medical Center · US

Funding

INTESTINAL VITAMIN H UPTAKE--MOLECULAR/CELL REGULATIONR01DK058057 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 2000 to 2019
$6.8M
Functional architecture of IP3-evoked local Ca2+ signalsR01GM088790 · NIGMS · UNIVERSITY OF MINNESOTA · PI MARCHANT, JONATHAN S, SLAMA, JAMES T · 2009 to 2025
$4.7M
Mechanism/Regulation of Intestinal Thiamin UptakeR37DK056061 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SAID, HAMID M · 2009 to 2018
$3.6M
Physiology/pathophysiology of intestinal vitC uptake: Cell/molecular mechanismsR01DK107474 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SUBRAMANIAN, VEEDAMALI S · 2016 to 2020
$2.1M
Physiological and Pathological Aspects of Intestinal Vitamin B2 AbsorptionI01BX001142 · VA · VETERANS HEALTH ADMINISTRATION · PI HAMID M SAID · 2011 to 2026
–
BLRD VA I01 BX001142NIDDK NIH HHS R01 DK058057NIDDK NIH HHS R01 DK107474NIDDK NIH HHS R37 DK056061NIGMS NIH HHS R01 GM088790
6 · The paper itself

Abstract

Mammalian cells utilize two transporters for the uptake of ascorbic acid (AA), Na

Indexed as

Gene Expression RegulationAdolescentAdultAnimalsColonDNA MethylationFemaleHumansJejunumMaleMiceMiddle AgedOrgan SpecificityPromoter Regions, GeneticSodium-Coupled Vitamin C TransportersYoung AdultSodium-Coupled Vitamin C Transportersdifferential expressionintestineSVCT-1SVCT-2uptakevitamin C

Identifiers

PMID27932501
PMCPMC5407060
OpenAlexW2560075488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.