Evidence map›Paper›PMID 27932481›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Modeling Monogenic Human Nephrotic Syndrome in the

Tobias Hermle, Daniela A Braun, Martin Helmstädter, Tobias B Huber, Friedhelm Hildebrandt

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 97 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Life of a Kidney Podocyte.Acta physiologica (Oxford, England) · 2025
    Review
  6. Article
  7. Review
  8. A Drug Screening Platform for Podocytopathies in Drosophila Nephrocytes.Journal of the American Society of Nephrology : JASN · 2025
    Article
  9. Discovery of a Small Molecule with an Inhibitory Role for RAB11.International journal of molecular sciences · 2024
    Article
  10. Article
  11. Article
  12. Drosophila Nephrocyte as a Model for Studying Glomerular Basement Membrane Physiology.Journal of the American Society of Nephrology : JASN · 2024
    Article
  13. Linking Basement Membrane and Slit Diaphragm in Drosophila Nephrocytes.Journal of the American Society of Nephrology : JASN · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. AbioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Article
  20. Insights into human kidney function from the study of Drosophila.Pediatric nephrology (Berlin, Germany) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Tobias HermleDivision of Nephrology, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts; tobias.hermle@childrens.harvard.edu friedhelm.hildebrandt@childrens.harvard.edu.
Daniela A BraunDivision of Nephrology, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Martin HelmstädterRenal Division, University Medical Center Freiburg, Freiburg, Germany, Faculty of Medicine, University of Freiburg, Freiburg, Germany; and.
Tobias B HuberRenal Division, University Medical Center Freiburg, Freiburg, Germany, Faculty of Medicine, University of Freiburg, Freiburg, Germany; and.
Friedhelm HildebrandtDivision of Nephrology, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts; tobias.hermle@childrens.harvard.edu friedhelm.hildebrandt@childrens.harvard.edu.
Boston Children's Hospital · USUniversity Medical Center Freiburg · DEHarvard University · US

Funding

Identification and function of new genes causing childhood nephrotic syndromeR01DK076683 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HILDEBRANDT, FRIEDHELM · 2007 to 2021
$5.3M
Exon capture and large-scale sequencing for disease-cause identification, early dRC1DK086542 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HILDEBRANDT, FRIEDHELM · 2009 to 2010
$981k
NIDDK NIH HHS R01 DK076683NIDDK NIH HHS RC1 DK086542
6 · The paper itself

Abstract

Steroid-resistant nephrotic syndrome is characterized by podocyte dysfunction.

Indexed as

Models, BiologicalNephrotic SyndromeAnimalsDrosophilaDrosophila ProteinsHumansNerve Tissue ProteinsDrosophila ProteinsNerve Tissue Proteinssli protein, DrosophilaCOQ2Drosophilagarland cellnephrocytenephrotic syndromeSRNS

Identifiers

PMID27932481
PMCPMC5407722
OpenAlexW2559859124

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.