Evidence map›Paper›PMID 27932475›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Intercalated Cell Depletion and Vacuolar H

Rizwan Mumtaz, Francesco Trepiccione, J Christopher Hennings, Antje K Huebner, Bettina Serbin, Nicolas Picard, A K M Shahid Ullah, Teodor G Păunescu, Diane E Capen, Rawad M Lashhab and 7 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 52 citations in OpenAlex.

  1. eLife · 2026
    Article
  2. Article
  3. State of knowledge on ammonia handling by the kidney.Pflugers Archiv : European journal of physiology · 2024
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Renal Tubular Acidosis: HAdvances in chronic kidney disease · 2018
    Review
  19. Article
  20. Mouse models of SLC4-linked disorders of HCOAmerican journal of physiology. Cell physiology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 6 countries.

Rizwan MumtazInstitute of Human Genetics, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Francesco TrepiccioneInstitut National de la Santé et de la Recherche Médicale U970, Paris Cardiovascular Research Center, Paris Descartes University, Department of Physiology, Hôpital Européen Georges Pompidou, Paris, France.
J Christopher HenningsInstitute of Human Genetics, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Antje K HuebnerInstitute of Human Genetics, Jena University Hospital, Friedrich Schiller University, Jena, Germany.
Bettina SerbinInstitut National de la Santé et de la Recherche Médicale U970, Paris Cardiovascular Research Center, Paris Descartes University, Department of Physiology, Hôpital Européen Georges Pompidou, Paris, France.
Nicolas PicardCentre National de la Recherche Scientifique, Équipe de Recherche Labellisée 8228, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche en Santé 1138, Centre de Recherche des Cordeliers, Université Pierre et Marie Curie, Paris, France.
A K M Shahid UllahDepartment of Physiology, University of Alberta, Edmonton, Alberta, Canada.
Teodor G PăunescuCenter for Systems Biology, Program in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and.
Diane E CapenCenter for Systems Biology, Program in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and.
Rawad M LashhabDepartment of Physiology, University of Alberta, Edmonton, Alberta, Canada.
Isabelle Mouro-ChanteloupInstitut National de la Transfusion Sanguine, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche en Santé 1134, Laboratory of Excellence Globule Rouge-Excellence, Paris Diderot University, Paris, France.
Seth L AlperNephrology Division and Vascular Biology Research Center, Beth Israel Deaconess Medical Center, Department of Medicine, Harvard Medical School, Boston, Massachusetts.
Carsten A WagnerInstitute of Physiology, University of Zurich, Zurich, Switzerland; and.
Emmanuelle CordatDepartment of Physiology, University of Alberta, Edmonton, Alberta, Canada.
Dennis BrownCenter for Systems Biology, Program in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and.
Dominique EladariService de Physiologie Explorations Fonctionnelles Rénales, Centre Hospitalier Universitaire de la Réunion, Hôpital Felix Guyon; and dominique.eladari@inserm.fr christian.huebner@med.uni-jena.de.
Christian A HübnerInstitute of Human Genetics, Jena University Hospital, Friedrich Schiller University, Jena, Germany; dominique.eladari@inserm.fr christian.huebner@med.uni-jena.de.
Massachusetts General Hospital · USUniversity of Alberta · CAFriedrich Schiller University Jena · DEInserm · FRJena University Hospital · DEBeth Israel Deaconess Medical Center · USCentre Hospitalier Universitaire de La Réunion · FRParis Cardiovascular Research Center · FRUniversité Paris Cité · FRUniversity of Zurich · CH

Funding

Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3M
Transgenic CoreP30DK057521 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI KAHN, BARBARA B. · 2000 to 2019
$31.4M
Regulation of proton pump trafficking in kidneyR37DK042956 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BROWN, DENNIS · 2008 to 2017
$4.0M
CELLULAR REGULATION OF KIDNEY EPITHELIAL CELL POLARITYR01DK042956 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BROWN, DENNIS · 1991 to 2006
$2.2M
Regulation of proton pump trafficking in kidneyR56DK042956 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BROWN, DENNIS · 2018 to 2018
$100k
NIDDK NIH HHS P30 DK043351NIDDK NIH HHS P30 DK057521NIDDK NIH HHS R01 DK042956NIDDK NIH HHS R37 DK042956NIDDK NIH HHS R56 DK042956
6 · The paper itself

Abstract

Distal nephron acid secretion is mediated by highly specialized type A intercalated cells (A-ICs), which contain vacuolar H

Indexed as

Acidosis, Renal TubularAnimalsAnion Exchange Protein 1, ErythrocyteKidney Tubules, CollectingMaleMiceModels, BiologicalVacuolar Proton-Translocating ATPasesAnion Exchange Protein 1, ErythrocyteVacuolar Proton-Translocating ATPasesCell & Transport Physiologychronic metabolic acidosisdistal tubulegenetic renal diseaseion transporttransgenic mouse

Identifiers

PMID27932475
PMCPMC5407715
OpenAlexW2560310448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.