Evidence map›Paper›PMID 27932380›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

Absence of vitamin D receptor (VDR)-mediated PPARγ suppression causes alopecia in VDR-null mice.

Vaibhav Saini, Hengguang Zhao, Elizabeth T Petit, Francesca Gori, Marie B Demay

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Functional hair follicle regeneration: an updated review.Signal transduction and targeted therapy · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vaibhav SainiEndocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Hengguang ZhaoEndocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Elizabeth T PetitEndocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Francesca GoriEndocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Marie B DemayEndocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA demay@helix.mgh.harvard.edu.
Harvard University · USMassachusetts General Hospital · US

Funding

VITAMIN D RECEPTOR ABLATION: DIRECT AND INDIRECT CONSEQUENCESR01DK046974 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI DEMAY, MARIE · 1993 to 2015
$5.0M
Skeletal Phenotyping CoreP30AR066261 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI KRONENBERG, HENRY M. · 2014 to 2018
$3.5M
NIAMS NIH HHS P30 AR066261NIDDK NIH HHS R01 DK046974
6 · The paper itself

Abstract

Vitamin D receptor (VDR) mutations in humans and mice cause alopecia. VDR-null (VDR

Indexed as

Adult Stem CellsAlopeciaAnimalsCells, CulturedChromosomal Proteins, Non-HistoneHaploinsufficiencyKeratinocytesLipoprotein LipaseMiceNuclear ProteinsPPAR gammaProtein BindingReceptors, CalcitriolRepressor ProteinsTranscription FactorsUp-RegulationChromosomal Proteins, Non-HistoneDppa3 protein, mouseLipoprotein LipaseNuclear ProteinsPPAR gammaPpargc1b protein, mouseReceptors, CalcitriolRepressor ProteinsTranscription Factorshair cyclekeratinocyte stem cellmouse modelvitamin D–resistant rickets

Identifiers

PMID27932380
PMCPMC5295732
OpenAlexW2560558577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.